Vitamin D3-¹³C₅  (Synonyms: Cholecalciferol-¹³C₅; Colecalciferol-¹³C₅)

Vitamin D3-¹³C₅ is the deuterium labeled Vitamin D3 (HY-15398). Vitamin D3 (Cholecalciferol) is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells[1][2].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

389.60

C₂₂¹³C₅H₄₄O

67-97-0

C=C1CC[C@H](O)C/C1=C/C=C2CCC[C@]3(C)[C@]([H])(CC[C@@]\23[H])[C@H](C)C[13CH2][13CH2][13CH]([13CH3])[13CH3]

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  [Content Brief]

  [2]. Yoshioka H, et al. Vitamin D3-induced hypercalcemia increases carbon tetrachloride-induced hepatotoxicity through elevated oxidative stress in mice. PLoS One. 2017 Apr 27;12(4):e0176524.  [Content Brief]