2. Vitamin D Related/Nuclear Receptor
  3. Androgen Receptor
  4. VPC-3033

VPC-3033 is an androgen receptor antagonist. VPC-3033 has a strong androgen DHT replacement potency (IC50: 0.625-2.5 μM), can effectively inhibit androgen receptor transcriptional activity (IC50=0.3 μM), and has a strong androgen receptor degradation ability. In addition, VPC-3033 exhibits significant anti-androgen receptor activity against prostate cancer cells resistant to Enzalutamide (HY-70002).

For research use only. We do not sell to patients.

VPC-3033 Chemical Structure

VPC-3033 Chemical Structure

CAS No. : 110763-24-1

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VPC-3033 Related Antibodies

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Description

VPC-3033 is an androgen receptor antagonist. VPC-3033 has a strong androgen DHT replacement potency (IC50: 0.625-2.5 μM), can effectively inhibit androgen receptor transcriptional activity (IC50=0.3 μM), and has a strong androgen receptor degradation ability. In addition, VPC-3033 exhibits significant anti-androgen receptor activity against prostate cancer cells resistant to Enzalutamide (HY-70002)[1].

Molecular Weight

298.33

Formula

C21H14O2
CAS No.
SMILES

O=C1C2=C(/C(C3=C1C=CC=C3)=C\C4=CC(O)=CC=C4)C=CC=C2
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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VPC-3033 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

VPC-3033110763-24-1VPC3033VPC 3033Androgen ReceptorAndrogen receptorantagonistinhibits transcriptiondegradationprostate cancer cellsInhibitorinhibitorinhibit

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HY-118409
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