VQPGQN(Phe-¹³C₉,¹⁵N)HMFTKEKLEEVIKDI TFA 

VQPGQN(Phe-¹³C9,¹⁵N)HMFTKEKLEEVIKDI (TFA) is the ¹³C and ¹⁵N labeled isotope of VQPGQN-HMFTKEKLEEVIKDI (TFA)^[1].

2640.94 (free acid)

C₁₁₀¹³C₉H₁₈₈N₂₉¹⁵NO₃₅S.xC₂HF₃O₂

Solid

White to off-white

Val-Gln-Pro-Gly-Gln-Asn-{Phe-13C9,15N}-His-Met-Phe-Thr-Lys-Glu-Lys-Leu-Glu-Glu-Val-Ile-Lys-Asp-Ile

VQPGQN-{Phe-13C9,15N}-HMFTKEKLEEVIKDI

O=C(N[C@@H](CCC(N)=O)C(N1[C@@H](CCC1)C(NCC(N[C@@H](CCC(N)=O)C(N[C@@H](CC(N)=O)C([15NH][13C@@H]([13CH2][13C]2=[13CH][13CH]=[13CH][13CH]=[13CH]2)[13C](N[C@@H](CC3=CNC=N3)C(N[C@@H](CCSC)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCCCN)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](C(C)C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCCN)C(N[C@@H](CC(O)=O)C(N[C@@H]([C@@H](C)CC)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C(C)C)N.O=C(C(F)(F)F)O.[x]

Room temperature in continental US; may vary elsewhere.

Sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

• [1]. Russak, et sl. Impact of deuterium substitution on the pharmacokinetics of pharmaceuticals. Annals of Pharmacotherapy 53.2 (2019): 211-223.  [Content Brief]