2. Anti-infection
  3. Bacterial
  4. VU0038882

VU0038882 is a small-molecule activator of coproporphyrinogen oxidase (CgoX). VU0038882 can activate CgoX from Gram-Positive bacteria in vitro. VU0038882 can be used for the research of skin and soft tissue infections (SSTIs) .

For research use only. We do not sell to patients.

VU0038882 Chemical Structure

VU0038882 Chemical Structure

CAS No. : 429653-28-1

Size Stock
50 mg   Get quote  
100 mg   Get quote  
250 mg   Get quote  
Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

VU0038882 Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

VU0038882 is a small-molecule activator of coproporphyrinogen oxidase (CgoX). VU0038882 can activate CgoX from Gram-Positive bacteria in vitro. VU0038882 can be used for the research of skin and soft tissue infections (SSTIs) [1].

In Vitro

VU0038882 (‘882) (40 μM) exposure leads to accumulation of CPIII in S. aureus[1].
VU0038882 (0-10 μM) activates CgoX from Gram-Positive bacteria in vitro[1].
VU0038882 (50 μM) induces photosensitivity in Gram-positive pathogens[1].
VU0038882 leads to massive heme accumulation resulting in HssRS activation in S. aureus[1].
VU0038882 leads to photosensitization of Gram-positive bacteria, reducing bacterial burdens in vivo[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

VU0038882 Related Antibodies
Molecular Weight

276.29

Formula

C17H12N2O2
CAS No.
SMILES

OC1=C2C=CC=CC2=CC=C1C3=NNC(C4=CC=CO4)=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

VU0038882 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

VU0038882429653-28-1VU 0038882VU-0038882Bacterialcoproporphyrinogen oxidase (CgoX)Gram-Positive bacteriaskinsoft tissue infections (SSTIs)Inhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
VU0038882
Cat. No.:
HY-118951
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.