1. Epigenetics
  2. Histone Methyltransferase
  3. WDR5-MYC-IN-1

WDR5-MYC-IN-1 (compound 4o) is a potent WDR5-MYC interaction inhibitor with a Ki value of 1.0 µM. WDR5-MYC-IN-1 shows antiproliferative activity.

For research use only. We do not sell to patients.

WDR5-MYC-IN-1 Chemical Structure

WDR5-MYC-IN-1 Chemical Structure

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Description

WDR5-MYC-IN-1 (compound 4o) is a potent WDR5-MYC interaction inhibitor with a Ki value of 1.0 µM. WDR5-MYC-IN-1 shows antiproliferative activity[1].

IC50 & Target

Ki: 1.0 µM (WDR5-MYC)[1]

In Vitro

WDR5-MYC-IN-1 (compound 4o) shows antiproliferative activity with IC50s of 1.52, 1.51, 2.20, 5.32, 7.40 µM for RAJI, RAMOS, SUDHL4, HL-60, H1299 cells, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Proliferation Assay[1]

Cell Line: RAJI, RAMOS, SUDHL4, HL-60, H1299 cells
Concentration:
Incubation Time:
Result: Showed antiproliferative activity with IC50s of 1.52, 1.51, 2.20, 5.32, 7.40 µM for RAJI, RAMOS, SUDHL4, HL-60, H1299 cells, respectively.
Molecular Weight

290.36

Formula

C12H10N4OS2

SMILES

O=C(NC)C1=CC=C(C2=C(SC#N)SC(N)=N2)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
WDR5-MYC-IN-1
Cat. No.:
HY-163774
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