2. Cell Cycle/DNA Damage
  3. Wee1
  4. WEE1-IN-11

WEE1-IN-11 (Compound 13) is a potent CDK2 inhibitor with an IC50 of 2.0 nM. WEE1-IN-11 inhibits NCI–H446, A427, OVCAR3, C33A,and WiDr cells with IC50s of 93.9, 34.5, 86.7, 23.1, and 85 nM, respectively.

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WEE1-IN-11 Chemical Structure

WEE1-IN-11 Chemical Structure

CAS No. : 2975172-98-4

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WEE1-IN-11 Related Antibodies

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Description

WEE1-IN-11 (Compound 13) is a potent CDK2 inhibitor with an IC50 of 2.0 nM. WEE1-IN-11 inhibits NCI–H446, A427, OVCAR3, C33A,and WiDr cells with IC50s of 93.9, 34.5, 86.7, 23.1, and 85 nM, respectively[1].

Molecular Weight

552.69

Formula

C26H29FN8OS2
CAS No.
SMILES

CN1CCN(C2=CC=C(NC3=NC=C(C4=CN=CS4)C(C5=CN=C(N6C[C@@H](F)CC6)S5)=N3)C=C2OC)CC1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
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References
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WEE1-IN-11 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

WEE1-IN-112975172-98-4Wee1GLX0198NCI–H446A427OVCAR3C33AWiDrInhibitorinhibitorinhibit

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