2. Metabolic Enzyme/Protease
  3. Carbonic Anhydrase
  4. WES-1

WES-1 (Compound 8g) is an inhibitor of carbonic anhydrase IX (Ki: 55.9 μM). WES-1 has broad spectrum anti-proliferative activity against the cancer cells, such as leukemia (K-562 and MOLT-4), non-small cell lung cancer (NCI–H460), colon cancer (HCT 116 and HCT-15) and melanoma (LOX IMVI) cell lines.

For research use only. We do not sell to patients.

WES-1 Chemical Structure

WES-1 Chemical Structure

CAS No. : 2748673-86-9

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WES-1 Related Antibodies

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Description

WES-1 (Compound 8g) is an inhibitor of carbonic anhydrase IX (Ki: 55.9 μM). WES-1 has broad spectrum anti-proliferative activity against the cancer cells, such as leukemia (K-562 and MOLT-4), non-small cell lung cancer (NCI–H460), colon cancer (HCT 116 and HCT-15) and melanoma (LOX IMVI) cell lines[1].

Molecular Weight

396.46

Formula

C20H20N4O3S
CAS No.
SMILES

O=C(NC1=C(S(=O)(N)=O)C=CC=C1)NC2=CC=C(C3=CC=C(C)C=C3)N=C2C
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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WES-1 Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

WES-12748673-86-9WES1WES 1Carbonic AnhydraseCarbonate dehydrataseleukemiaK-562MOLT-4)NSCLCNCI–H460colon cancerHCT 116HCT-15melanomaInhibitorinhibitorinhibit

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