2. GPCR/G Protein Neuronal Signaling
  3. Neurokinin Receptor
  4. WIN 66306

WIN 66306 is a cyclic heptapeptide that can be isolated from an Aspergillus species. WIN 66306 is a neurokinin antagonist with antagonistic effects on both NK1 and NK2 receptors.

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WIN 66306 Chemical Structure

WIN 66306 Chemical Structure

CAS No. : 151928-32-4

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WIN 66306 Related Antibodies

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Description

WIN 66306 is a cyclic heptapeptide that can be isolated from an Aspergillus species. WIN 66306 is a neurokinin antagonist with antagonistic effects on both NK1 and NK2 receptors[1][2].

Molecular Weight

800.90

Formula

C41H52N8O9
CAS No.
Sequence

Cyclo(Gly-Trp-Pro-Gly-Val-Gly-{(βR)-β-OH-3-(3-Me-2-Butenyl)-Tyr})
Sequence Shortening

Cyclo(GWPGVG-{(βR)-β-OH-3-(3-Me-2-Butenyl)-Tyr})
SMILES

O=C(N1[C@@](C(NCC(N[C@H](C(NCC(N[C@@](C(NCC(N2)=O)=O)([H])[C@@H](C3=CC(C/C=C(C)\C)=C(C=C3)O)O)=O)=O)C(C)C)=O)=O)([H])CCC1)[C@@H]2CC4=CNC5=CC=CC=C45
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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WIN 66306 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

WIN 66306151928-32-4WIN66306WIN-66306Neurokinin ReceptorNK receptorTachykinin receptorAspergillusneurokininInhibitorinhibitorinhibit

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