2. Cell Cycle/DNA Damage
  3. DNA/RNA Synthesis
  4. WRN inhibitor 11

WRN inhibitor 11 (Example 17) is an orally active inhibitor of WRN helicase, with the IC50 of 63 nM.

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WRN inhibitor 11 Chemical Structure

WRN inhibitor 11 Chemical Structure

CAS No. : 3058317-61-3

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WRN inhibitor 11 Related Antibodies

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Description

WRN inhibitor 11 (Example 17) is an orally active inhibitor of WRN helicase, with the IC50 of 63 nM[1].

Molecular Weight

742.15

Formula

C34H35ClF3N9O5
CAS No.
SMILES

CCC1=C(C(N2N=C(N=C2N1CC(NC3=CC(Cl)=C(C=C3C)C(F)(F)F)=O)C4=CCOCC4)=O)N5C6CN(C(C7=NC=NC(C)=C7O)=O)CC5CC6
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
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WRN inhibitor 11 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

WRN inhibitor 113058317-61-3WRN inhibitor11WRN inhibitor-11DNA/RNA SynthesisHCT116 cellsSW48 cellsLoVo cellsSW620 cellsInhibitorinhibitorinhibit

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