2. Epigenetics
  3. Epigenetic Reader Domain
  4. Y02224

Y02224 is a potent BRD4 inhibitor and exhibits reasonable antiproliferative effect on leukemia cells.Y02224 has the potential for? CRPC research.

For research use only. We do not sell to patients.

Y02224 Chemical Structure

Y02224 Chemical Structure

CAS No. : 1853988-48-3

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Y02224 Related Antibodies

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Description

Y02224 is a potent BRD4 inhibitor and exhibits reasonable antiproliferative effect on leukemia cells.Y02224 has the potential for? CRPC research[1].

IC50 & Target

IC50: BRD4[1]
Cellular Effect
Cell Line Type Value Description References
HL-60 IC50
2.99 μM
Compound: 85
Antiproliferative activity against human HL60 cells after 72 hrs by CCK8 assay
Antiproliferative activity against human HL60 cells after 72 hrs by CCK8 assay
[PMID: 26731490]
HT-29 IC50
12.9 μM
Compound: 85
Antiproliferative activity against human HT-29 cells after 72 hrs by CCK8 assay
Antiproliferative activity against human HT-29 cells after 72 hrs by CCK8 assay
[PMID: 26731490]
MV4-11 IC50
1.3 μM
Compound: 85
Antiproliferative activity against human MV4-11 cells after 72 hrs by CCK8 assay
Antiproliferative activity against human MV4-11 cells after 72 hrs by CCK8 assay
[PMID: 26731490]
Molecular Weight

461.33

Formula

C20H17BrN2O4S
CAS No.
SMILES

O=C1C2=C(C3=CC=C2)C(N1CC)=CC=C3NS(C4=C(C=CC(Br)=C4)OC)(=O)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Y02224 Related Classifications

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Keywords:

Y022241853988-48-3Y 02224Y-02224Epigenetic Reader DomainCastration-Resistant Prostate CancerCRPCBRD4,leukemia cellInhibitorinhibitorinhibit

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Y02224
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HY-114902
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