2. PROTAC Epigenetics
  3. PROTACs Epigenetic Reader Domain
  4. YDR1

YDR1 is a potent PROTAC SMARCA2 degrader, with the DC50 of 7.7 nM(Sturcture Note:(Blue: Cereblon ligand (HY-W087383), Black: linker；Pink: SMARCA2 ligand (HY-44012B)).

For research use only. We do not sell to patients.

YDR1 Chemical Structure

YDR1 Chemical Structure

CAS No. : 2951015-31-7

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YDR1 Related Antibodies

Top Publications Citing Use of Products

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von Hippel-Lindau (VHL) Cereblon MDM2 cIAP1

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Description

YDR1 is a potent PROTAC SMARCA2 degrader, with the DC50 of 7.7 nM(Sturcture Note:(Blue: Cereblon ligand (HY-W087383), Black: linker；Pink: SMARCA2 ligand (HY-44012B))[1].

Molecular Weight

816.92

Formula

C44H49FN10O5
CAS No.
SMILES

O=C(N(C1CCC(NC1=O)=O)C2=O)C3=C2C=CC(N4CCN(CC5CCN(C6=C(F)C=C(CN7CCN(C8=C(N)N=NC(C9=C(O)C=CC=C9)=C8)CC7)C=C6)CC5)CC4)=C3
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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YDR1 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

YDR12951015-31-7YDR 1YDR-1PROTACsEpigenetic Reader DomainsotorasibInhibitorinhibitorinhibit

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