2. Apoptosis
  3. Apoptosis
  4. YLT205

YLT205 is an anticancer agent and induces cell apoptosis. YLT205 inhibits tumor growth in vivo and in vitro.

For research use only. We do not sell to patients.

YLT205 Chemical Structure

YLT205 Chemical Structure

CAS No. : 1316196-63-0

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YLT205 Related Antibodies

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Description

YLT205 is an anticancer agent and induces cell apoptosis. YLT205 inhibits tumor growth in vivo and in vitro[1].

Cellular Effect
Cell Line Type Value Description References
A-431 IC50
20 nM
Compound: 159a
Antiproliferative activity against human A-431 cells assessed as reduction in cell viability incubated for 4 days by MTT assay
Antiproliferative activity against human A-431 cells assessed as reduction in cell viability incubated for 4 days by MTT assay
[PMID: 31926469]
A549 IC50
44 nM
Compound: 159a
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 4 days by MTT assay
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 4 days by MTT assay
[PMID: 31926469]
HepG2 IC50
48 nM
Compound: 159a
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 4 days by MTT assay
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 4 days by MTT assay
[PMID: 31926469]
SW-620 IC50
4.3 nM
Compound: 159a
Antiproliferative activity against human SW620 cells assessed as reduction in cell viability incubated for 4 days by MTT assay
Antiproliferative activity against human SW620 cells assessed as reduction in cell viability incubated for 4 days by MTT assay
[PMID: 31926469]
Molecular Weight

471.78

Formula

C16H12BrClN4O2S2
CAS No.
SMILES

O=C(CCl)NC1=CC2=C(N=C(SCC(NC3=NC=C(C=C3)Br)=O)S2)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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YLT205 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

YLT2051316196-63-0YLT 205YLT-205Apoptosiscolorectal cancerHCT116SW480Inhibitorinhibitorinhibit

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HY-117515
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