1. Protein Tyrosine Kinase/RTK
  2. c-Met/HGFR
  3. (Z)-Semaxanib

(Z)-Semaxanib (compound (z)-1) is a potent tyrosine kinase inhibitor. (Z)-Semaxanib shows cytotoxicity for TAMH and HepG2 cells with IC50s of 6.28 µM and 8.17 µM, respectively.

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(Z)-Semaxanib Chemical Structure

(Z)-Semaxanib Chemical Structure

CAS No. : 194413-58-6

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Description

(Z)-Semaxanib (compound (z)-1) is a potent tyrosine kinase inhibitor. (Z)-Semaxanib shows cytotoxicity for TAMH and HepG2 cells with IC50s of 6.28 µM and 8.17 µM, respectively[1].

Molecular Weight

238.29

Formula

C15H14N2O

CAS No.
SMILES

O=C(NC1=C/2C=CC=C1)C2=C/C3=C(C)C=C(C)N3

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Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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(Z)-Semaxanib
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HY-10332
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