2. Anti-infection
  3. Bacterial
  4. Ziapin 2

Ziapin 2 is a molecular optomechanical light transducer. Ziapin 2 is an amphiphilic azobenzene with a strong non-covalent affinity to the plasma membrane. Ziapin 2 can be used to photo-modulate the membrane potential in cells of the Gram-positive bacterium Bacillus subtilis. Ziapin 2 enters the lipid membrane very rapidly (≈ 40 ns).

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Ziapin 2 Chemical Structure

Ziapin 2 Chemical Structure

CAS No. : 2399497-60-8

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Description

Ziapin 2 is a molecular optomechanical light transducer. Ziapin 2 is an amphiphilic azobenzene with a strong non-covalent affinity to the plasma membrane. Ziapin 2 can be used to photo-modulate the membrane potential in cells of the Gram-positive bacterium Bacillus subtilis. Ziapin 2 enters the lipid membrane very rapidly (≈ 40 ns)[1][2].

Molecular Weight

778.70

Formula

C40H54Br2N6
CAS No.
Appearance

Solid

Color

Green to dark green

SMILES

N(CCCCCC[N+]1=CC=CC=C1)(C2=CC=C(C=C2)/N=N/C3=CC=C(N4CCCCCC4)C=C3)CCCCCC[N+]5=CC=CC=C5.[Br-].[Br-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (64.21 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.2842 mL 6.4210 mL 12.8419 mL
5 mM 0.2568 mL 1.2842 mL 2.5684 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.2842 mL 6.4210 mL 12.8419 mL 32.1048 mL
5 mM 0.2568 mL 1.2842 mL 2.5684 mL 6.4210 mL
10 mM 0.1284 mL 0.6421 mL 1.2842 mL 3.2105 mL
15 mM 0.0856 mL 0.4281 mL 0.8561 mL 2.1403 mL
20 mM 0.0642 mL 0.3210 mL 0.6421 mL 1.6052 mL
25 mM 0.0514 mL 0.2568 mL 0.5137 mL 1.2842 mL
30 mM 0.0428 mL 0.2140 mL 0.4281 mL 1.0702 mL
40 mM 0.0321 mL 0.1605 mL 0.3210 mL 0.8026 mL
50 mM 0.0257 mL 0.1284 mL 0.2568 mL 0.6421 mL
60 mM 0.0214 mL 0.1070 mL 0.2140 mL 0.5351 mL
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Ziapin 2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ziapin 22399497-60-8Ziapin2Ziapin-2BacterialBacillus subtilisHEK293Inhibitorinhibitorinhibit

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