2. Vitamin D Related/Nuclear Receptor
  3. Thyroid Hormone Receptor
  4. ZTA-261

ZTA-261 is a highly selective and low toxic thyroid hormone receptor β subtype (THR-β) agonist (IC50=6.3 nM) that reduces body weight and visceral fat through a liothyronine (HY-A0070A) mediated pathway. ZTA-261 can be used in the study of lipid metabolism and obesity prevalence.

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ZTA-261 Chemical Structure

ZTA-261 Chemical Structure

CAS No. : 3049368-51-3

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ZTA-261 Related Antibodies

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Description

ZTA-261 is a highly selective and low toxic thyroid hormone receptor β subtype (THR-β) agonist (IC50=6.3 nM) that reduces body weight and visceral fat through a liothyronine (HY-A0070A) mediated pathway. ZTA-261 can be used in the study of lipid metabolism and obesity prevalence[1].

IC50 & Target

IC50：6.3 nM (THR-β) [1]
Molecular Weight

428.32

Formula

C21H14F6O3
CAS No.
SMILES

O=C(CC1=CC(C(F)(F)F)=C(CC2=CC=C(C3=C2C=CC=C3)O)C(C(F)(F)F)=C1)O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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ZTA-261 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ZTA-2613049368-51-3ZTA261ZTA 261Thyroid Hormone ReceptorTHRThyroid hormone receptoragonistlipid metabolismobesityT3Inhibitorinhibitorinhibit

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ZTA-261
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HY-163945
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