2. Metabolic Enzyme/Protease
  3. Glucosidase Phosphatase Amylases
  4. α-glucosidase/PTP1B-IN-1

α-glucosidase/PTP1B-IN-1 (compound 8a) is a potent α-glucosidase and PTP1B inhibitor with an IC50 value of 66.3 μM and 47.0 μM, respectively. α-glucosidase/PTP1B-IN-1 exhibits excellent activities against α-amylase with an IC50 of 30.62 μM. α-glucosidase/PTP1B-IN-1 can dock into the active pockets of α-glucosidase and PTP1B. α-glucosidase/PTP1B-IN-1 has potential to reduce the postprandial blood glucose and is used for Type 2 diabetes mellitus.

For research use only. We do not sell to patients.

α-glucosidase/PTP1B-IN-1 Chemical Structure

α-glucosidase/PTP1B-IN-1 Chemical Structure

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α-glucosidase/PTP1B-IN-1 Related Antibodies

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Description

α-glucosidase/PTP1B-IN-1 (compound 8a) is a potent α-glucosidase and PTP1B inhibitor with an IC50 value of 66.3 μM and 47.0 μM, respectively. α-glucosidase/PTP1B-IN-1 exhibits excellent activities against α-amylase with an IC50 of 30.62 μM. α-glucosidase/PTP1B-IN-1 can dock into the active pockets of α-glucosidase and PTP1B. α-glucosidase/PTP1B-IN-1 has potential to reduce the postprandial blood glucose and is used for Type 2 diabetes mellitus[1].

Molecular Weight

447.31

Formula

C23H20Cl2O5
SMILES

ClC1=CC(Cl)=C(/C=C/C(OCCOC2=CC(C)=C3C(OC(C(C)=C3C)=O)=C2)=O)C=C1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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α-glucosidase/PTP1B-IN-1 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

α-glucosidase/PTP1B-IN-1GlucosidasePhosphataseAmylasesα-glucosidase,α-amylaseblood glucoseType 2 diabetes mellitusInhibitorinhibitorinhibit

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