α-Hydroxyglutaric acid (disodium) (Standard)

Cat. No.: HY-113038AR Purity: ≥98%: FAQs
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Ophiopogonin D (Standard) is the analytical standard of Ophiopogonin D. This product is intended for research and analytical applications. Ophiopogonin D, isolated from the tubers of Ophiopogon japonicus, is a rare naturally occurring C29 steroidal glycoside. Ophiopogonin D is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation, IκBα down-regulation, intracellular Ca2+ overload and activation of pro-inflammatory cytokines by increasing the expression of CYP2J2/EETs and PPARα in human umbilical vein endothelial cells (HUVECs). Ophiopogonin D has been used to treat inflammatory and cardiovascular diseases for thousands of years.

For research use only. We do not sell to patients.

α-Hydroxyglutaric acid (disodium) (Standard) Chemical Structure

CAS No. : 40951-21-1

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Description	Ophiopogonin D (Standard) is the analytical standard of Ophiopogonin D. This product is intended for research and analytical applications. Ophiopogonin D, isolated from the tubers of Ophiopogon japonicus, is a rare naturally occurring C29 steroidal glycoside. Ophiopogonin D is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation, IκBα down-regulation, intracellular Ca2+ overload and activation of pro-inflammatory cytokines by increasing the expression of CYP2J2/EETs and PPARα in human umbilical vein endothelial cells (HUVECs). Ophiopogonin D has been used to treat inflammatory and cardiovascular diseases for thousands of years.
Molecular Weight	192.08
Formula	C₅H₆Na₂O₅
CAS No.	40951-21-1
SMILES	O=C(O[Na])C(O)CCC(O[Na])=O
Structure Classification	Ketones, Aldehydes, Acids
Initial Source	Endogenous metabolite
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Handling Instructions (2659 KB)

α-Hydroxyglutaric acid (disodium) (Standard) Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

α-Hydroxyglutaric acid (disodium) (Standard)40951-21-1Histone DemethylaseEndogenous MetaboliteCell-permeable5-methylcytosineα-ketoglutaratedioxygenasesIDH1IDH2Inhibitorinhibitorinhibit

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α-Hydroxyglutaric acid (disodium) (Standard)

Product Information

Purity & Documentation

Customer Review

α-Hydroxyglutaric acid (disodium) (Standard) Related Classifications

Molarity Calculator

Dilution Calculator