2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. α-Muricholic acid

α-Muricholic acid is the most abundant primary bile acid in rodents.

For research use only. We do not sell to patients.

α-Muricholic acid Chemical Structure

α-Muricholic acid Chemical Structure

CAS No. : 2393-58-0

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Based on 1 publication(s) in Google Scholar

Other Forms of α-Muricholic acid:

α-Muricholic acid Related Antibodies

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Description

α-Muricholic acid is the most abundant primary bile acid in rodents[1][2].

In Vivo

Sulfated and non-sulfated bile acids are determined in the intestines and in the feces of 7-month-old germ-free and conventional male mice. The major bile acids from germ-free mice are cholic acid, α-Muricholic acid and β-Muricholic acid[1].
In the context of primary bile acid, α-Muricholic acid is greatly reduced in high-fat diet (HFD)-soybean protein isolate (SPI) mice compared to the HFD controls[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

408.57

Formula

C24H40O5
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@@]([C@]1([H])[C@H](O)[C@H]2O)(CC[C@@H](O)C1)[C@]3([H])[C@]2([H])[C@@](CC[C@]4([H])[C@H](C)CCC(O)=O)([H])[C@]4(C)CC3
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMF : 30 mg/mL (73.43 mM; Need ultrasonic and warming)

DMSO : ≥ 20 mg/mL (48.95 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4476 mL 12.2378 mL 24.4756 mL
5 mM 0.4895 mL 2.4476 mL 4.8951 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥98.0%

COA (250 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / DMF 1 mM 2.4476 mL 12.2378 mL 24.4756 mL 61.1890 mL
5 mM 0.4895 mL 2.4476 mL 4.8951 mL 12.2378 mL
10 mM 0.2448 mL 1.2238 mL 2.4476 mL 6.1189 mL
15 mM 0.1632 mL 0.8159 mL 1.6317 mL 4.0793 mL
20 mM 0.1224 mL 0.6119 mL 1.2238 mL 3.0595 mL
25 mM 0.0979 mL 0.4895 mL 0.9790 mL 2.4476 mL
30 mM 0.0816 mL 0.4079 mL 0.8159 mL 2.0396 mL
40 mM 0.0612 mL 0.3059 mL 0.6119 mL 1.5297 mL
DMF 50 mM 0.0490 mL 0.2448 mL 0.4895 mL 1.2238 mL
60 mM 0.0408 mL 0.2040 mL 0.4079 mL 1.0198 mL
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α-Muricholic acid Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

α-Muricholic acid2393-58-0Endogenous MetabolitePrimarybilerodentsInhibitorinhibitorinhibit

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