1. Neuronal Signaling
  2. α-synuclein
  3. α-Synuclein 4554W

α-Synuclein 4554W is an inhibitor of α-Synuclein (aSyn) aggregation with associated toxicity. α-Synuclein 4554W consists of GIVNGVKA sequences, previously identified through intracellular library screening. α-Synuclein 4554W reduces fibril formation of aSyn mutants assocaited with Parkinson’s disease.

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α-Synuclein 4554W Chemical Structure

α-Synuclein 4554W Chemical Structure

CAS No. : 2243207-00-1

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Description

α-Synuclein 4554W is an inhibitor of α-Synuclein (aSyn) aggregation with associated toxicity. α-Synuclein 4554W consists of GIVNGVKA sequences, previously identified through intracellular library screening. α-Synuclein 4554W reduces fibril formation of aSyn mutants assocaited with Parkinson’s disease[1].

Molecular Weight

1041.20

Formula

C45H80N14O14

CAS No.
Sequence

Ac-Lys-Asp-Gly-Ile-Val-Asn-Gly-Val-Lys-Ala-NH2

Sequence Shortening

Ac-KDGIVNGVKA-NH2

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α-Synuclein 4554W
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HY-P5082
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