αGalCer-RBD 

αGalCer-RBD is a self-adjuvanting lipoprotein conjugate. αGalCer-RBD induces potent immunity against SARS-CoV-2 and its variants of concern. αGalCer-RBD conjugate induces RBD-specific, cytokine-producing T cell development. αGalCer-RBD has great potential to be an effective COVID-19 vaccine candidate. α-Galactosylceramide (αGalCer) is a potent invariant natural killer T cell (iNKT) agonist^[1]. RBD: receptor-binding domain

The first time conjugates the iNKT cell agonist on the protein antigen, and the resulting αGalCer-RBD conjugate anchored on liposomes biomimicking the virus capsid structure remarkably enhances the protective immune response against SARS-CoV-2^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

αGalCer-RBD enhances the immune efficacy of the adjuvant and produces significantly stronger humoral responses and cellular responses in mice^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

1119.60

C₆₀H₁₁₈N₄O₁₄

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Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Wang J, et al. Self-Adjuvanting Lipoprotein Conjugate αGalCer-RBD Induces Potent Immunity against SARS-CoV-2 and its Variants of Concern. J Med Chem. 2022;65(3):2558-2570.  [Content Brief]