1. Membrane Transporter/Ion Channel
  2. Sodium Channel
  3. δ-Buthitoxin-Hj1a

δ-Buthitoxin-Hj1a, a scorpion-venom peptide, is a potent NaV1.1 agonist with an EC50 of 17nM. δ-Buthitoxin-Hj1a can be used for the Dravet syndrome (DS) research.

For research use only. We do not sell to patients.

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δ-Buthitoxin-Hj1a Chemical Structure

δ-Buthitoxin-Hj1a Chemical Structure

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Description

δ-Buthitoxin-Hj1a, a scorpion-venom peptide, is a potent NaV1.1 agonist with an EC50 of 17nM. δ-Buthitoxin-Hj1a can be used for the Dravet syndrome (DS) research[1].

IC50 & Target[1]

Nav1.1

17 nM (EC50)

Molecular Weight

7482.39

Formula

C326H482N92O96S8

Sequence

Glu-Glu-Val-Arg-Asp-Ala-Tyr-Ile-Ala-Gln-Pro-His-Asn-Cys-Val-Tyr-His-Cys-Phe-Arg-Asp-Ser-Tyr-Cys-Asn-Asp-Leu-Cys-Ile-Lys-His-Gly-Ala-Glu-Ser-Gly-Glu-Cys-Lys-Trp-Phe-Thr-Ser-Ser-Gly-Asn-Ala-Cys-Trp-Cys-Val-Lys-Leu-Pro-Lys-Ser-Glu-Pro-Ile-Lys-Val-Pro-Gly-Lys-Cys-His (Disulfide bridge:Cys14-Cys65;Cys18-Cys38;Cys24-Cys48;Cys28-Cys50)

Sequence Shortening

EEVRDAYIAQPHNCVYHCFRDSYCNDLCIKHGAESGECKWFTSSGNACWCVKLPKSEPIKVPGKCH (Disulfide bridge:Cys14-Cys65;Cys18-Cys38;Cys24-Cys48;Cys28-Cys50)

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
δ-Buthitoxin-Hj1a
Cat. No.:
HY-P5784
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