2. Membrane Transporter/Ion Channel
  3. Sodium Channel
  4. δ-Buthitoxin-Hj1a

δ-Buthitoxin-Hj1a, a scorpion-venom peptide, is a potent NaV1.1 agonist with an EC50 of 17nM. δ-Buthitoxin-Hj1a can be used for the Dravet syndrome (DS) research.

For research use only. We do not sell to patients.

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δ-Buthitoxin-Hj1a Chemical Structure

δ-Buthitoxin-Hj1a Chemical Structure

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δ-Buthitoxin-Hj1a Related Antibodies

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Description

δ-Buthitoxin-Hj1a, a scorpion-venom peptide, is a potent NaV1.1 agonist with an EC50 of 17nM. δ-Buthitoxin-Hj1a can be used for the Dravet syndrome (DS) research[1].

IC50 & Target[1]

Nav1.1

17 nM (EC50)

Molecular Weight

7482.39

Formula

C326H482N92O96S8
Sequence

Glu-Glu-Val-Arg-Asp-Ala-Tyr-Ile-Ala-Gln-Pro-His-Asn-Cys-Val-Tyr-His-Cys-Phe-Arg-Asp-Ser-Tyr-Cys-Asn-Asp-Leu-Cys-Ile-Lys-His-Gly-Ala-Glu-Ser-Gly-Glu-Cys-Lys-Trp-Phe-Thr-Ser-Ser-Gly-Asn-Ala-Cys-Trp-Cys-Val-Lys-Leu-Pro-Lys-Ser-Glu-Pro-Ile-Lys-Val-Pro-Gly-Lys-Cys-His (Disulfide bridge:Cys14-Cys65;Cys18-Cys38;Cys24-Cys48;Cys28-Cys50)
Sequence Shortening

EEVRDAYIAQPHNCVYHCFRDSYCNDLCIKHGAESGECKWFTSSGNACWCVKLPKSEPIKVPGKCH (Disulfide bridge:Cys14-Cys65;Cys18-Cys38;Cys24-Cys48;Cys28-Cys50)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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δ-Buthitoxin-Hj1a Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

δ-Buthitoxin-Hj1aSodium ChannelNa channelsNa+ channelsNaV1.1scorpion-venom peptideDravet syndromeInhibitorinhibitorinhibit

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