1. Membrane Transporter/Ion Channel
  2. Sodium Channel
  3. δ-Theraphotoxin-Hm1b

δ-Theraphotoxin-Hm1b is a 42-amino acid peptide isolated from Togo starburst tarantula (Heteroscodra maculata) venom. δ-Theraphotoxin-Hm1b selectively inhibits inactivation of NaV1.1 but have no effect on NaV1.7.

For research use only. We do not sell to patients.

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δ-Theraphotoxin-Hm1b Chemical Structure

δ-Theraphotoxin-Hm1b Chemical Structure

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Description

δ-Theraphotoxin-Hm1b is a 42-amino acid peptide isolated from Togo starburst tarantula (Heteroscodra maculata) venom. δ-Theraphotoxin-Hm1b selectively inhibits inactivation of NaV1.1 but have no effect on NaV1.7[1].

Molecular Weight

3895.38

Formula

C169H241N45O50S6

Sequence

Glu-Cys-Arg-Tyr-Leu-Phe-Gly-Gly-Cys-Lys-Thr-Thr-Ala-Asp-Cys-Cys-Lys-His-Leu-Gly-Cys-Arg-Thr-Asp-Leu-Tyr-Tyr-Cys-Ala-Trp-Asp-Gly-Thr-Phe (Disulfide bridge:Cys2-Cys16;Cys9-Cys21;Cys15-Cys28)

Sequence Shortening

ECRYLFGGCKTTADCCKHLGCRTDLYYCAWDGTF (Disulfide bridge:Cys2-Cys16;Cys9-Cys21;Cys15-Cys28)

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
δ-Theraphotoxin-Hm1b
Cat. No.:
HY-P5781
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