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  3. 1,10-Decanediol

1,10-Decanediol is a diol compound that can react with α-ketoglutarate (aKG) to generate polymeric microparticles (termed paKG MPs) for the sustained release of aKG, thereby promoting immunosuppressive regulation. Additionally, paKG MPs can bind to dendritic cells (DCs), reducing their glycolysis and mitochondrial respiration in vitro. These metabolic changes lead to the modulation of MHC-II and CD86 expression in DCs and alter the frequency of regulatory T cells (Tregs) as well as T-helper type 1/2/17 cells in vitro. 1,10-Decanediol can be used in research within the field of immunometabolism.

For research use only. We do not sell to patients.

1,10-Decanediol Chemical Structure

1,10-Decanediol Chemical Structure

CAS No. : 112-47-0

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10 mM * 1 mL in DMSO USD 55 In-stock
Solid
500 mg USD 50 In-stock
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Description

1,10-Decanediol is a diol compound that can react with α-ketoglutarate (aKG) to generate polymeric microparticles (termed paKG MPs) for the sustained release of aKG, thereby promoting immunosuppressive regulation. Additionally, paKG MPs can bind to dendritic cells (DCs), reducing their glycolysis and mitochondrial respiration in vitro. These metabolic changes lead to the modulation of MHC-II and CD86 expression in DCs and alter the frequency of regulatory T cells (Tregs) as well as T-helper type 1/2/17 cells in vitro. 1,10-Decanediol can be used in research within the field of immunometabolism[1].

Molecular Weight

174.28

Formula

C10H22O2

CAS No.
Appearance

Solid

SMILES

OCCCCCCCCCCO

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Room temperature in continental US; may vary elsewhere.

Storage

Store at room temperature

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1,10-Decanediol Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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1,10-Decanediol
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HY-W016773
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