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  6. 1,3,5,6-Tetrahydroxyxanthone

1,3,5,6-Tetrahydroxyxanthone is a natural xanthone that can be isolated from Garcinia achachairu Rusby (Clusiaceae) branches. 1,3,5,6-Tetrahydroxyxanthone induces diuresis and saluresis in normotensive and hypertensive rats.

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1,3,5,6-Tetrahydroxyxanthone Chemical Structure

1,3,5,6-Tetrahydroxyxanthone Chemical Structure

CAS No. : 5084-31-1

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1,3,5,6-Tetrahydroxyxanthone Related Antibodies

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Description

1,3,5,6-Tetrahydroxyxanthone is a natural xanthone that can be isolated from Garcinia achachairu Rusby (Clusiaceae) branches. 1,3,5,6-Tetrahydroxyxanthone induces diuresis and saluresis in normotensive and hypertensive rats[1].

Cellular Effect
Cell Line Type Value Description References
A549 IC50
10 mg/mL
Compound: 16
Cytotoxicity against human A549 cells after 3 days by SRB assay
Cytotoxicity against human A549 cells after 3 days by SRB assay
[PMID: 15568778]
HCT-116 IC50
18.6 μM
Compound: Table S1, R269C2
Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay
Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay
[PMID: 30684866]
HeLa S3 IC50
> 10 μM
Compound: 22
Cytotoxicity in human HeLaS3 cells incubated for 72 hrs by MTT assay
Cytotoxicity in human HeLaS3 cells incubated for 72 hrs by MTT assay
[PMID: 30978023]
HepG2 IC50
> 10 μM
Compound: 22
Cytotoxicity in human HepG2 cells incubated for 72 hrs by MTT assay
Cytotoxicity in human HepG2 cells incubated for 72 hrs by MTT assay
[PMID: 30978023]
HT-29 IC50
> 10 μM
Compound: 22
Cytotoxicity in human HT-29 cells incubated for 72 hrs by MTT assay
Cytotoxicity in human HT-29 cells incubated for 72 hrs by MTT assay
[PMID: 30978023]
KB IC50
> 10 μM
Compound: 22
Cytotoxicity in human KB cells incubated for 72 hrs by MTT assay
Cytotoxicity in human KB cells incubated for 72 hrs by MTT assay
[PMID: 30978023]
MCF7 IC50
> 10 μM
Compound: 22
Cytotoxicity in human MCF7 cells incubated for 72 hrs by MTT assay
Cytotoxicity in human MCF7 cells incubated for 72 hrs by MTT assay
[PMID: 30978023]
MCF7 IC50
9.3 mg/mL
Compound: 16
Cytotoxicity against human MCF7 cells after 3 days by SRB assay
Cytotoxicity against human MCF7 cells after 3 days by SRB assay
[PMID: 15568778]
Molecular Weight

260.20

Formula

C13H8O6
CAS No.
SMILES

O=C1C2=C(OC3=C1C=CC(O)=C3O)C=C(O)C=C2O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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1,3,5,6-Tetrahydroxyxanthone Related Classifications

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

1,3,5,6-Tetrahydroxyxanthone5084-31-1Othersnatural productxanthoneGarcinia achachairudiuresissaluresisratSHRNTRInhibitorinhibitorinhibit

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