1-Hydroxypyrene-d₉

Name: 1-Hydroxypyrene-d 9
Brand: MedChemExpress
SKU: HY-W014075S
Rating: 4.5 (1 reviews)

Cat. No.: HY-W014075S Purity: 99.95%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

1-Hydroxypyrene-d₉ is the deuterium labeled 1-Hydroxypyrene[1]. 1-Hydroxypyrene, a biomarker of exposure to polycyclic aromatic hydrocarbons (PAHs), is analyzed in urine samples. 1-Hydroxypyrene is the major biomarker of exposure to pyrenes[2].

For research use only. We do not sell to patients.

1-Hydroxypyrene-d<sub>9</sub> Chemical Structure

1-Hydroxypyrene-d₉ Chemical Structure

CAS No. : 132603-37-3

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of 1-Hydroxypyrene-d₉:

1-Hydroxypyrene Get quote

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Purity & Documentation
References
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Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

227.31

Formula

C₁₆HD₉O

CAS No.

132603-37-3

Unlabeled CAS

5315-79-7

Appearance

Solid

Color

White to off-white

SMILES

OC1=C2C3=C4C(C([2H])=C2[2H])=C([2H])C([2H])=C([2H])C4=C([2H])C([2H])=C3C([2H])=C1[2H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (219.96 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.3993 mL	21.9964 mL	43.9928 mL
5 mM	0.8799 mL	4.3993 mL	8.7986 mL
10 mM	0.4399 mL	2.1996 mL	4.3993 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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mg/kg

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.95%

Select Batch:

Data Sheet (279 KB) SDS (251 KB)

COA (258 KB) HNMR (260 KB) RP-HPLC (819 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

[2]. Fernando Freitas, et al. Urinary 1-hydroxypyrene Is Associated With Oxidative Stress and Inflammatory Biomarkers in Acute Myocardial Infarction. Int J Environ Res Public Health [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.3993 mL	21.9964 mL	43.9928 mL	109.9820 mL
	5 mM	0.8799 mL	4.3993 mL	8.7986 mL	21.9964 mL
	10 mM	0.4399 mL	2.1996 mL	4.3993 mL	10.9982 mL
	15 mM	0.2933 mL	1.4664 mL	2.9329 mL	7.3321 mL
	20 mM	0.2200 mL	1.0998 mL	2.1996 mL	5.4991 mL
	25 mM	0.1760 mL	0.8799 mL	1.7597 mL	4.3993 mL
	30 mM	0.1466 mL	0.7332 mL	1.4664 mL	3.6661 mL
	40 mM	0.1100 mL	0.5499 mL	1.0998 mL	2.7495 mL
	50 mM	0.0880 mL	0.4399 mL	0.8799 mL	2.1996 mL
	60 mM	0.0733 mL	0.3666 mL	0.7332 mL	1.8330 mL
	80 mM	0.0550 mL	0.2750 mL	0.5499 mL	1.3748 mL
	100 mM	0.0440 mL	0.2200 mL	0.4399 mL	1.0998 mL