1-Nitrosopyrrolidine-d₈

Name: 1-Nitrosopyrrolidine-d 8
Brand: MedChemExpress
SKU: HY-W141077S
Rating: 4.5 (1 reviews)

Cat. No.: HY-W141077S Purity: 99.40%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

1-Nitrosopyrrolidine-d₈ is deuterium labeled 1-Nitrosopyrrolidine.

For research use only. We do not sell to patients.

1-Nitrosopyrrolidine-d<sub>8</sub> Chemical Structure

1-Nitrosopyrrolidine-d₈ Chemical Structure

CAS No. : 1219802-09-1

Size	Price	Stock	Quantity
1 mg	USD 85	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 210	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 350	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of 1-Nitrosopyrrolidine-d₈:

1-Nitrosopyrrolidine Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

1-Nitrosopyrrolidine-d₈ is deuterium labeled 1-Nitrosopyrrolidine.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

108.17

Formula

C₄D₈N₂O

CAS No.

1219802-09-1

Appearance

Liquid

Color

Colorless to light yellow

SMILES

[2H]C1([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])N1N=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (924.47 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	9.2447 mL	46.2235 mL	92.4471 mL
5 mM	1.8489 mL	9.2447 mL	18.4894 mL
10 mM	0.9245 mL	4.6224 mL	9.2447 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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mg/kg

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.40%

Select Batch:

Data Sheet (278 KB) SDS (393 KB)

COA (259 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	9.2447 mL	46.2235 mL	92.4471 mL	231.1177 mL
	5 mM	1.8489 mL	9.2447 mL	18.4894 mL	46.2235 mL
	10 mM	0.9245 mL	4.6224 mL	9.2447 mL	23.1118 mL
	15 mM	0.6163 mL	3.0816 mL	6.1631 mL	15.4078 mL
	20 mM	0.4622 mL	2.3112 mL	4.6224 mL	11.5559 mL
	25 mM	0.3698 mL	1.8489 mL	3.6979 mL	9.2447 mL
	30 mM	0.3082 mL	1.5408 mL	3.0816 mL	7.7039 mL
	40 mM	0.2311 mL	1.1556 mL	2.3112 mL	5.7779 mL
	50 mM	0.1849 mL	0.9245 mL	1.8489 mL	4.6224 mL
	60 mM	0.1541 mL	0.7704 mL	1.5408 mL	3.8520 mL
	80 mM	0.1156 mL	0.5778 mL	1.1556 mL	2.8890 mL
	100 mM	0.0924 mL	0.4622 mL	0.9245 mL	2.3112 mL