11-Deoxy Prostaglandin E2

Cat. No.: HY-114910 Purity: ≥99.0%: FAQs
Data Sheet SDS COA Handling Instructions Technical Support

11-Deoxy Prostaglandin E2 is a selective agonist of EP4 with an EC₅₀ of 0.66 nM. 11-Deoxy Prostaglandin E2 is an analog of prostaglandin E2. 11-Deoxy Prostaglandin E2 can be used in study bone healing, heart failure, and other receptor associated conditions.

For research use only. We do not sell to patients.

11-Deoxy Prostaglandin E2 Chemical Structure

CAS No. : 35536-53-9

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

336.47

Formula

C₂₀H₃₂O₄

CAS No.

35536-53-9

Appearance

Solid

Color

White to off-white

SMILES

CCCCC[C@@H](/C=C/[C@@H](CCC1=O)[C@H]1C/C=C\CCCC(O)=O)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (297.20 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.9720 mL	14.8602 mL	29.7203 mL
5 mM	0.5944 mL	2.9720 mL	5.9441 mL
10 mM	0.2972 mL	1.4860 mL	2.9720 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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In Vivo Dissolution Calculator

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥99.0%

Select Batch:

Data Sheet (273 KB) SDS (557 KB)

COA (252 KB)

Handling Instructions (2659 KB)

References

[1]. Holt MC, et al. Improved homology modeling of the human & rat EP4 prostanoid receptors. BMC Mol Cell Biol. 2019 Aug 27;20(1):37. [Content Brief]

[2]. Ungrin MD, et al. Key structural features of prostaglandin E(2) and prostanoid analogs involved in binding and activation of the human EP(1) prostanoid receptor. Mol Pharmacol. 2001 Jun;59(6):1446-56. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.9720 mL	14.8602 mL	29.7203 mL	74.3008 mL
	5 mM	0.5944 mL	2.9720 mL	5.9441 mL	14.8602 mL
	10 mM	0.2972 mL	1.4860 mL	2.9720 mL	7.4301 mL
	15 mM	0.1981 mL	0.9907 mL	1.9814 mL	4.9534 mL
	20 mM	0.1486 mL	0.7430 mL	1.4860 mL	3.7150 mL
	25 mM	0.1189 mL	0.5944 mL	1.1888 mL	2.9720 mL
	30 mM	0.0991 mL	0.4953 mL	0.9907 mL	2.4767 mL
	40 mM	0.0743 mL	0.3715 mL	0.7430 mL	1.8575 mL
	50 mM	0.0594 mL	0.2972 mL	0.5944 mL	1.4860 mL
	60 mM	0.0495 mL	0.2477 mL	0.4953 mL	1.2383 mL
	80 mM	0.0372 mL	0.1858 mL	0.3715 mL	0.9288 mL
	100 mM	0.0297 mL	0.1486 mL	0.2972 mL	0.7430 mL