15-Keto-prostaglandin E2-d₉

Cat. No.: HY-113205S: FAQs
Data Sheet Handling Instructions

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15-Keto-prostaglandin E2-d₉ is the deuterium labeled 15-Keto-prostaglandin E2[1].

For research use only. We do not sell to patients.

15-Keto-prostaglandin E2-d<sub>9</sub> Chemical Structure

15-Keto-prostaglandin E2-d₉ Chemical Structure

Size		Stock
1 mg		Get quote	Estimated Time of Arrival: December 31
5 mg		Get quote	Estimated Time of Arrival: December 31

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This product is a controlled substance and not for sale in your territory.

Other Forms of 15-Keto-prostaglandin E2-d₉:

15-keto-Prostaglandin E2 Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

15-Keto-prostaglandin E2-d₉ is the deuterium labeled 15-Keto-prostaglandin E2[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

359.50

Formula

C₂₀H₂₁D₉O₅

Unlabeled CAS

26441-05-4

SMILES

O=C1[C@@H]([C@H]([C@@H](C1)O)/C=C/C(CC([2H])(C([2H])(C([2H])(C([2H])([2H])[2H])[2H])[2H])[2H])=O)C/C=C\CCCC(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility

In Vitro:

DMSO : ≥ 100 mg/mL (278.16 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.7816 mL	13.9082 mL	27.8164 mL
5 mM	0.5563 mL	2.7816 mL	5.5633 mL
10 mM	0.2782 mL	1.3908 mL	2.7816 mL

View the Complete Stock Solution Preparation Table

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.7816 mL	13.9082 mL	27.8164 mL	69.5410 mL
	5 mM	0.5563 mL	2.7816 mL	5.5633 mL	13.9082 mL
	10 mM	0.2782 mL	1.3908 mL	2.7816 mL	6.9541 mL
	15 mM	0.1854 mL	0.9272 mL	1.8544 mL	4.6361 mL
	20 mM	0.1391 mL	0.6954 mL	1.3908 mL	3.4771 mL
	25 mM	0.1113 mL	0.5563 mL	1.1127 mL	2.7816 mL
	30 mM	0.0927 mL	0.4636 mL	0.9272 mL	2.3180 mL
	40 mM	0.0695 mL	0.3477 mL	0.6954 mL	1.7385 mL
	50 mM	0.0556 mL	0.2782 mL	0.5563 mL	1.3908 mL
	60 mM	0.0464 mL	0.2318 mL	0.4636 mL	1.1590 mL
	80 mM	0.0348 mL	0.1739 mL	0.3477 mL	0.8693 mL
	100 mM	0.0278 mL	0.1391 mL	0.2782 mL	0.6954 mL