1. Antibody-drug Conjugate/ADC Related
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  3. 18-Azido-stearic acid

18-Azido-stearic acid is a click chemistry reagent containing an azide group. 18-Azido-stearic acid can be used as a hydrophobic bioconjugation linker (using N-Myristoyltransferase) that can be further modified at the azido-position using Click-chemistry. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

For research use only. We do not sell to patients.

18-Azido-stearic acid Chemical Structure

18-Azido-stearic acid Chemical Structure

CAS No. : 1529763-58-3

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5 mg USD 100 In-stock
10 mg USD 160 In-stock
25 mg USD 320 In-stock
50 mg USD 480 In-stock
100 mg USD 720 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

18-Azido-stearic acid is a click chemistry reagent containing an azide group. 18-Azido-stearic acid can be used as a hydrophobic bioconjugation linker (using N-Myristoyltransferase) that can be further modified at the azido-position using Click-chemistry[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

Molecular Weight

325.49

Formula

C18H35N3O2

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)CCCCCCCCCCCCCCCCCN=[N+]=[N-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (307.23 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0723 mL 15.3615 mL 30.7229 mL
5 mM 0.6145 mL 3.0723 mL 6.1446 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥95.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0723 mL 15.3615 mL 30.7229 mL 76.8073 mL
5 mM 0.6145 mL 3.0723 mL 6.1446 mL 15.3615 mL
10 mM 0.3072 mL 1.5361 mL 3.0723 mL 7.6807 mL
15 mM 0.2048 mL 1.0241 mL 2.0482 mL 5.1205 mL
20 mM 0.1536 mL 0.7681 mL 1.5361 mL 3.8404 mL
25 mM 0.1229 mL 0.6145 mL 1.2289 mL 3.0723 mL
30 mM 0.1024 mL 0.5120 mL 1.0241 mL 2.5602 mL
40 mM 0.0768 mL 0.3840 mL 0.7681 mL 1.9202 mL
50 mM 0.0614 mL 0.3072 mL 0.6145 mL 1.5361 mL
60 mM 0.0512 mL 0.2560 mL 0.5120 mL 1.2801 mL
80 mM 0.0384 mL 0.1920 mL 0.3840 mL 0.9601 mL
100 mM 0.0307 mL 0.1536 mL 0.3072 mL 0.7681 mL
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18-Azido-stearic acid Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
18-Azido-stearic acid
Cat. No.:
HY-151692
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