18β-Glycyrrhetyl-3-O-sulfate-d₂ (Synonyms: Glycyrrhetic acid 3-O-hydrogen sulfate-d₂)

Cat. No.: HY-148682S1: FAQs
Data Sheet Handling Instructions

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18β-Glycyrrhetyl-3-O-sulfate-d₂ is the deuterium labeled 18β-Glycyrrhetyl-3-O-sulfate (HY-148682)[1].

For research use only. We do not sell to patients.

18β-Glycyrrhetyl-3-O-sulfate-d<sub>2</sub> Chemical Structure

18β-Glycyrrhetyl-3-O-sulfate-d₂ Chemical Structure

Size		Stock
1 mg		Get quote	Estimated Time of Arrival: December 31

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This product is a controlled substance and not for sale in your territory.

Other Forms of 18β-Glycyrrhetyl-3-O-sulfate-d₂:

18β-Glycyrrhetyl-3-O-sulfate In-stock
18β-Glycyrrhetyl-3-O-sulfate-d₃ Get quote

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Description

18β-Glycyrrhetyl-3-O-sulfate-d₂ is the deuterium labeled 18β-Glycyrrhetyl-3-O-sulfate (HY-148682)[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

552.76

Formula

C₃₀H₄₄D₂O₇S

Unlabeled CAS

10251-38-4

SMILES

C[C@]12[C@]3(C([C@@]4([H])[C@@](CC3)(CC[C@@](C)(C4)C(O)=O)C)=CC([C@]1([H])[C@@]5([C@@](C(C)([C@H](C([2H])([2H])C5)OS(=O)(O)=O)C)([H])CC2)C)=O)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility

In Vitro:

DMSO : ≥ 100 mg/mL (180.91 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.8091 mL	9.0455 mL	18.0910 mL
5 mM	0.3618 mL	1.8091 mL	3.6182 mL
10 mM	0.1809 mL	0.9046 mL	1.8091 mL

View the Complete Stock Solution Preparation Table

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-237. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.8091 mL	9.0455 mL	18.0910 mL	45.2276 mL
	5 mM	0.3618 mL	1.8091 mL	3.6182 mL	9.0455 mL
	10 mM	0.1809 mL	0.9046 mL	1.8091 mL	4.5228 mL
	15 mM	0.1206 mL	0.6030 mL	1.2061 mL	3.0152 mL
	20 mM	0.0905 mL	0.4523 mL	0.9046 mL	2.2614 mL
	25 mM	0.0724 mL	0.3618 mL	0.7236 mL	1.8091 mL
	30 mM	0.0603 mL	0.3015 mL	0.6030 mL	1.5076 mL
	40 mM	0.0452 mL	0.2261 mL	0.4523 mL	1.1307 mL
	50 mM	0.0362 mL	0.1809 mL	0.3618 mL	0.9046 mL
	60 mM	0.0302 mL	0.1508 mL	0.3015 mL	0.7538 mL
	80 mM	0.0226 mL	0.1131 mL	0.2261 mL	0.5653 mL
	100 mM	0.0181 mL	0.0905 mL	0.1809 mL	0.4523 mL

18β-Glycyrrhetyl-3-O-sulfate-d₂ Related Classifications

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

18β-Glycyrrhetyl-3-O-sulfate-d₂Glycyrrhetic acid 3-O-hydrogen sulfate-d₂Isotope-Labeled CompoundsInhibitorinhibitorinhibit

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18β-Glycyrrhetyl-3-O-sulfate-d2 (Synonyms: Glycyrrhetic acid 3-O-hydrogen sulfate-d2)

Other Forms of 18β-Glycyrrhetyl-3-O-sulfate-d2:

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