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  4. Neoboutonia macrocalyx Pax
  5. 2,3,8-Tri-O-methylellagic acid

2,3,8-Tri-O-methylellagic acid  (Synonyms: 3,3′,4-Tri-O-methylellagic acid)

Cat. No.: HY-N1652
Handling Instructions

2,3,8-Tri-O-methylellagic acid is a terpenoids that can be isolated from the stem bark of Neoboutonia macrocalyx. 2,3,8-Tri-O-methylellagic acid is found to be 50 times more active than the parent ellagic acid.

For research use only. We do not sell to patients.

2,3,8-Tri-O-methylellagic acid Chemical Structure

2,3,8-Tri-O-methylellagic acid Chemical Structure

CAS No. : 1617-49-8

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Description

2,3,8-Tri-O-methylellagic acid is a terpenoids that can be isolated from the stem bark of Neoboutonia macrocalyx. 2,3,8-Tri-O-methylellagic acid is found to be 50 times more active than the parent ellagic acid[1][2].

Cellular Effect
Cell Line Type Value Description References
Col2 ED50
> 5 μg/mL
Compound: 10
Cytotoxicity against human Col2 cells after 72 hrs by sulforhodamine B assay
Cytotoxicity against human Col2 cells after 72 hrs by sulforhodamine B assay
[PMID: 18271551]
HT-29 IC50
> 10 μM
Compound: S3
Inhibition of mitochondrial membrane potential in human HT-29 cells after 3 hrs by JC-1 staining based fluorescence assay
Inhibition of mitochondrial membrane potential in human HT-29 cells after 3 hrs by JC-1 staining based fluorescence assay
[PMID: 30057155]
HT-29 IC50
> 10 μM
Compound: S3
Cytotoxicity against human HT-29 cells assessed as reduction in cell viability after 72 hrs by CellTiter 96 aqueous one solution assay
Cytotoxicity against human HT-29 cells assessed as reduction in cell viability after 72 hrs by CellTiter 96 aqueous one solution assay
[PMID: 30057155]
KB ED50
> 5 μg/mL
Compound: 10
Cytotoxicity against human KB cells after 72 hrs by sulforhodamine B assay
Cytotoxicity against human KB cells after 72 hrs by sulforhodamine B assay
[PMID: 18271551]
Lu1 ED50
> 5 μg/mL
Compound: 10
Cytotoxicity against human Lu1 cells after 72 hrs by sulforhodamine B assay
Cytotoxicity against human Lu1 cells after 72 hrs by sulforhodamine B assay
[PMID: 18271551]
MCF7 ED50
> 5 μg/mL
Compound: 10
Cytotoxicity against human MCF7 cells after 72 hrs by sulforhodamine B assay
Cytotoxicity against human MCF7 cells after 72 hrs by sulforhodamine B assay
[PMID: 18271551]
MDA-MB-435 IC50
> 10 μM
Compound: S3
Cytotoxicity against human MDA-MB-435 cells assessed as reduction in cell viability after 72 hrs by CellTiter 96 aqueous one solution assay
Cytotoxicity against human MDA-MB-435 cells assessed as reduction in cell viability after 72 hrs by CellTiter 96 aqueous one solution assay
[PMID: 30057155]
OVCAR-3 IC50
> 10 μM
Compound: S3
Cytotoxicity against human OVCAR3 cells assessed as reduction in cell viability after 72 hrs by CellTiter 96 aqueous one solution assay
Cytotoxicity against human OVCAR3 cells assessed as reduction in cell viability after 72 hrs by CellTiter 96 aqueous one solution assay
[PMID: 30057155]
P388 ED50
> 5 μg/mL
Compound: 10
Cytotoxicity against mouse P388 cells after 72 hrs by sulforhodamine B assay
Cytotoxicity against mouse P388 cells after 72 hrs by sulforhodamine B assay
[PMID: 18271551]
Molecular Weight

344.27

Formula

C17H12O8

CAS No.
SMILES

O=C1C2=CC(OC)=C(OC)C(O3)=C2C4=C(C3=O)C=C(O)C(OC)=C4O1

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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  • Molarity Calculator

  • Dilution Calculator

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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2,3,8-Tri-O-methylellagic acid
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HY-N1652
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