2',3'-cGAMP-d₈ ammonium (Synonyms: 2'-3'-Cyclic GMP-AMP-d₈ ammonium)

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2',3'-cGAMP-d₈ (2'-3'-Cyclic GMP-AMP-d₈) ammonium is deuterium labeled 2',3'-cGAMP (ammonium).

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2',3'-cGAMP-d<sub>8</sub> ammonium Chemical Structure

2',3'-cGAMP-d₈ ammonium Chemical Structure

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Other Forms of 2',3'-cGAMP-d₈ ammonium:

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Description	2',3'-cGAMP-d₈ (2'-3'-Cyclic GMP-AMP-d₈) ammonium is deuterium labeled 2',3'-cGAMP (ammonium)^[1].
Molecular Weight	716.52
Formula	C₂₀H₂₂D₈N₁₂O₁₃P₂
SMILES	O=P1(O[C@@]2([2H])[C@H]([C@@H](O[C@@]2(C([2H])(OP(O[C@]3([C@@H](O[C@]([2H])(C([2H])(O1)[2H])[C@]3(O)[2H])N4C=NC5=C4NC(N)=NC5=O)[H])([O-])=O)[2H])[2H])N6C=NC7=C6N=CN=C7N)O)[O-].[NH4+].[NH4+]
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (272 KB) Handling Instructions (2659 KB)
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

2',3'-cGAMP-d₈ ammonium Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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2',3'-cGAMP-d₈2'-3'-Cyclic GMP-AMP-d₈Isotope-Labeled CompoundsInhibitorinhibitorinhibit

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2',3'-cGAMP-d8 ammonium (Synonyms: 2'-3'-Cyclic GMP-AMP-d8 ammonium)

Other Forms of 2',3'-cGAMP-d8 ammonium:

2',3'-cGAMP-d8 ammonium Related Antibodies

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2',3'-cGAMP-d8 ammonium Related Classifications