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  4. 2,6-Dithiopurine

2,6-Dithiopurine  (Synonyms: 2,6-Dimercaptopurine)

Cat. No.: HY-W016286 Purity: ≥98.0%
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2,6-Dithiopurine (2,6-Dimercaptopurine) is a nucleophilic scavenger for electrophilic carcinogens. 2,6-Dithiopurine abolishes both DNA adduct formation and the initiation of carcinogenesis.

For research use only. We do not sell to patients.

2,6-Dithiopurine Chemical Structure

2,6-Dithiopurine Chemical Structure

CAS No. : 5437-25-2

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Solid
1 g Get quote
5 g   Get quote  
10 g   Get quote  

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Based on 1 publication(s) in Google Scholar

2,6-Dithiopurine Related Antibodies

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Description

2,6-Dithiopurine (2,6-Dimercaptopurine) is a nucleophilic scavenger for electrophilic carcinogens. 2,6-Dithiopurine abolishes both DNA adduct formation and the initiation of carcinogenesis[1].

Molecular Weight

184.24

Formula

C5H4N4S2
CAS No.
Appearance

Solid

Color

Light brown to brown

SMILES

S=C(N1)NC2=C(N=CN2)C1=S
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (542.77 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.4277 mL 27.1385 mL 54.2770 mL
5 mM 1.0855 mL 5.4277 mL 10.8554 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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mg/kg

Animal weight
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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.4277 mL 27.1385 mL 54.2770 mL 135.6926 mL
5 mM 1.0855 mL 5.4277 mL 10.8554 mL 27.1385 mL
10 mM 0.5428 mL 2.7139 mL 5.4277 mL 13.5693 mL
15 mM 0.3618 mL 1.8092 mL 3.6185 mL 9.0462 mL
20 mM 0.2714 mL 1.3569 mL 2.7139 mL 6.7846 mL
25 mM 0.2171 mL 1.0855 mL 2.1711 mL 5.4277 mL
30 mM 0.1809 mL 0.9046 mL 1.8092 mL 4.5231 mL
40 mM 0.1357 mL 0.6785 mL 1.3569 mL 3.3923 mL
50 mM 0.1086 mL 0.5428 mL 1.0855 mL 2.7139 mL
60 mM 0.0905 mL 0.4523 mL 0.9046 mL 2.2615 mL
80 mM 0.0678 mL 0.3392 mL 0.6785 mL 1.6962 mL
100 mM 0.0543 mL 0.2714 mL 0.5428 mL 1.3569 mL
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2,6-Dithiopurine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2,6-Dithiopurine5437-25-22,6-DimercaptopurineOthersnucleophilic scavengerelectrophilic carcinogenInhibitorinhibitorinhibit

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