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  3. Biochemical Assay Reagents
  4. 2,6-Dithiopurine

2,6-Dithiopurine  (Synonyms: 2,6-Dimercaptopurine)

Cat. No.: HY-W016286 Purity: ≥98.0%
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2,6-Dithiopurine (2,6-Dimercaptopurine) is a nucleophilic scavenger for electrophilic carcinogens. 2,6-Dithiopurine abolishes both DNA adduct formation and the initiation of carcinogenesis.

For research use only. We do not sell to patients.

2,6-Dithiopurine Chemical Structure

2,6-Dithiopurine Chemical Structure

CAS No. : 5437-25-2

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Solid
1 g In-stock
5 g   Get quote  
10 g   Get quote  

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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

2,6-Dithiopurine Related Antibodies

Top Publications Citing Use of Products

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Description

2,6-Dithiopurine (2,6-Dimercaptopurine) is a nucleophilic scavenger for electrophilic carcinogens. 2,6-Dithiopurine abolishes both DNA adduct formation and the initiation of carcinogenesis[1].

Molecular Weight

184.25

Formula

C5H4N4S2
CAS No.
Appearance

Solid

Color

Light brown to brown

SMILES

S=C(N1)NC2=C(N=CN2)C1=S
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (542.74 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.4274 mL 27.1372 mL 54.2744 mL
5 mM 1.0855 mL 5.4274 mL 10.8549 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.4274 mL 27.1372 mL 54.2744 mL 135.6860 mL
5 mM 1.0855 mL 5.4274 mL 10.8549 mL 27.1372 mL
10 mM 0.5427 mL 2.7137 mL 5.4274 mL 13.5686 mL
15 mM 0.3618 mL 1.8091 mL 3.6183 mL 9.0457 mL
20 mM 0.2714 mL 1.3569 mL 2.7137 mL 6.7843 mL
25 mM 0.2171 mL 1.0855 mL 2.1710 mL 5.4274 mL
30 mM 0.1809 mL 0.9046 mL 1.8091 mL 4.5229 mL
40 mM 0.1357 mL 0.6784 mL 1.3569 mL 3.3921 mL
50 mM 0.1085 mL 0.5427 mL 1.0855 mL 2.7137 mL
60 mM 0.0905 mL 0.4523 mL 0.9046 mL 2.2614 mL
80 mM 0.0678 mL 0.3392 mL 0.6784 mL 1.6961 mL
100 mM 0.0543 mL 0.2714 mL 0.5427 mL 1.3569 mL
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2,6-Dithiopurine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2,6-Dithiopurine5437-25-22,6-DimercaptopurineBiochemical Assay Reagentsnucleophilic scavengerelectrophilic carcinogenInhibitorinhibitorinhibit

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