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  4. 2-Amino-5-fluorobenzoic acid

2-Amino-5-fluorobenzoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

For research use only. We do not sell to patients.

2-Amino-5-fluorobenzoic acid Chemical Structure

2-Amino-5-fluorobenzoic acid Chemical Structure

CAS No. : 446-08-2

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Based on 1 publication(s) in Google Scholar

2-Amino-5-fluorobenzoic acid Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

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Description

2-Amino-5-fluorobenzoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

In Vitro

2-Amino-5-fluorobenzoic acid is a toxic antitimetabolite for the tryptophan pathway in yeast that can be used to counterselect for TRP1, a commonly used genetic marker in S. cerevisiae. Because this trp1 strain lacks the enzymes required for the conversion of anthr anilic acid to tryptophan, it is resistant to 2-amino-5-fluorobenzoic acid feedback inhibition, enabling a growth-based, positive selection of the TRP1 marker. 2-Amino-5-fluorobenzoic acid is frequently used in genetic procedures that involve plasma manip calculations .

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

2-Amino-5-fluorobenzoic acid Related Antibodies
Molecular Weight

155.13

Formula

C7H6FNO2
CAS No.
Appearance

Solid

Color

Off-white to light brown

SMILES

O=C(O)C1=CC(F)=CC=C1N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (644.62 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.4462 mL 32.2310 mL 64.4621 mL
5 mM 1.2892 mL 6.4462 mL 12.8924 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.90%

SDS (393 KB)

COA (249 KB) HNMR (120 KB) RP-HPLC (199 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 6.4462 mL 32.2310 mL 64.4621 mL 161.1552 mL
5 mM 1.2892 mL 6.4462 mL 12.8924 mL 32.2310 mL
10 mM 0.6446 mL 3.2231 mL 6.4462 mL 16.1155 mL
15 mM 0.4297 mL 2.1487 mL 4.2975 mL 10.7437 mL
20 mM 0.3223 mL 1.6116 mL 3.2231 mL 8.0578 mL
25 mM 0.2578 mL 1.2892 mL 2.5785 mL 6.4462 mL
30 mM 0.2149 mL 1.0744 mL 2.1487 mL 5.3718 mL
40 mM 0.1612 mL 0.8058 mL 1.6116 mL 4.0289 mL
50 mM 0.1289 mL 0.6446 mL 1.2892 mL 3.2231 mL
60 mM 0.1074 mL 0.5372 mL 1.0744 mL 2.6859 mL
80 mM 0.0806 mL 0.4029 mL 0.8058 mL 2.0144 mL
100 mM 0.0645 mL 0.3223 mL 0.6446 mL 1.6116 mL
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2-Amino-5-fluorobenzoic acid Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2-Amino-5-fluorobenzoic acid446-08-2Biochemical Assay Reagentsbiochemical reagentbiological materialorganic compoundlife scienceInhibitorinhibitorinhibit

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