2. Biochemical Assay Reagents
  3. Gene Sequencing and Synthesis

Gene Sequencing and Synthesis

Nucleic acids are present in all living organisms and are categorized into two major types: ribonucleic acid (RNA) and deoxyribonucleic acid (DNA). They serves as a carrier of genetic material,with DNA and RNA encode genetic information through nucleic acid sequences, thereby directing protein synthesis. Consequently, nucleic acids are the foundation of biological research.
MCE provides a variety of nucleic acid synthesis raw materials, including modified nucleotide materials, which can be used for nucleic acid biosynthesis, labeling, and gene sequencing.

 

Gene Sequencing and Synthesis (153):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-114364
    UDP-Galactose disodium 137868-52-1 99.42%
    UDP-Galactose disodium is a natural agonist of the P2Y14 receptor with an EC50 of 0.67 μM for the hP2Y14 receptor. UDP-Galactose disodium is a substrate for the transferase beta-1, 4 galactosyltransferase V (B4GALT5). In addition, UDP-Galactose disodium is required for the biosynthesis of several abundant glycoconjugates that form the surface glycocalyx of Leishmania major.
    UDP-Galactose disodium
  • HY-112582C
    N1-Methylpseudouridine-5′-triphosphate trisodium solution (100mM) 99.70%
    N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) trisodium solution (100mM) is a nucleobase-modified nucleotide. N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) trisodium solution (100mM) is used for synthesizing mRNA with reduced immunogenicity and improved stability.
    N1-Methylpseudouridine-5′-triphosphate trisodium solution (100mM)
  • HY-114365
    UDP-GalNAc disodium 108320-87-2 99.98%
    UDP-GalNAc (UDP-N-acetyl-D-galactosamine) disodium is a sugar nucleotide and a substrate for EpsC115. EpsC115 is a mutant with N-terminal residues 1-115 deleted from the exopolymeric substance (EPS). UDP-GalNAc disodium is a donor substrate for many N-acetylgalactosaminyltransferases, which transfer GalNAc from nucleotide sugars to sugar or peptide acceptors. UDP-GalNAc disodium provides a sugar group donor for glycosylation reactions. UDP-GalNAc disodium can be used in cancer research, such as colorectal and breast cancer.
    UDP-GalNAc disodium
  • HY-130777A
    AMP-PNP lithium hydrate
    AMP-PNP lithium hydrate is a non-hydrolyzable analog of ATP. AMP-PNP can replace ATP for biological research and is not hydrolyzed by intracellular enzymes. In the study of BtuCD-F, a vitamin B12 transporter, it was found that AMP-PNP can block the channel formed by the two BtuCDs of the BtuCD-F complex, thereby preventing the entry of vitamin B12.
    AMP-PNP lithium hydrate
  • HY-40293
    N,N-Bis(trifluoromethylsulfonyl)aniline 37595-74-7 99.97%
    N,N-Bis(trifluoromethylsulfonyl)aniline (N-Phenyltrifluoromethanesulfonimide) is a sulfonylation reagent. N,N-Bis(trifluoromethylsulfonyl)aniline can be used for the synthesis of organic compounds.
    N,N-Bis(trifluoromethylsulfonyl)aniline
  • HY-170224
    dNTP Mixture,10 mM Solution,PCR Grade ≥99.0%
    dNTP Mixture, 10 mM Solution, PCR Grade is an equimolar mixture of dATP, dGTP, dCTP, and dTTP, suitable for amplification reactions of biology applications including PCR.
    dNTP Mixture,10 mM Solution,PCR Grade
  • HY-173246
    GalNAc-NAG25 phosphoramidite 2130036-52-9
    GalNAc-NAG-25 phosphoramidite is a phosphoramidite derivative containing N-acetylgalactosamine (GalNAc) part linked to NAG, which can be used for the synthesis of oligonucleotides.
    GalNAc-NAG25 phosphoramidite
  • HY-173247
    GalNAc-NAG37 phosphoramidite 2199491-27-3
    GalNAc-NAG37 phosphoramidite, a N-acetylgalactosamine (GalNAc) derivative, is a ligand of asialoglycoprotein receptor (ASGPR). GalNAc-NAG37 phosphoramidite can be used to synthesize GalNAc-siRNA and can be used for oligonucleotide delivery.
    GalNAc-NAG37 phosphoramidite
  • HY-156262
    DEPC-Treated Water
    DEPC-Treated Water is ultrapure water that has been sterilized by high temperature and high pressure and does not contain nuclease. It can avoid contamination by non-specific endonucleases and exonucleases and does not affect RNase activity.
    DEPC-Treated Water
  • HY-145974A
    m7GpppAmpG ammonium 99.50%
    m7GpppAmpG ammonium (m7G(5')ppp(5')(2'OMeA)pG ammonium) is a trinucleotide 5′ end cap analog. m7GpppAmpG ammonium binds to eIF4E with a KD value of 45.6 nM. m7GpppAmpG ammonium caps RNA with a capping efficiency of 90%. m7GpppAmpG ammonium enhances mRNA stability and translation efficiency. m7GpppAmpG ammonium is used in mRNA therapeutic research.
    m7GpppAmpG ammonium
  • HY-W013715A
    Deoxythymidine-5'-triphosphate (trisodium) solution (100mM) 27821-54-1 98.06%
    Deoxythymidine-5'-triphosphate (dTTP) trisodium solution (100mM) is one of the four nucleoside triphosphates used in the synthesis of DNA.
    Deoxythymidine-5'-triphosphate (trisodium) solution (100mM)
  • HY-W008661
    Deoxyguanosine triphosphate (trisodium) solution (100mM) 93919-41-6 99.95%
    Deoxyguanosine triphosphate (dGTP) trisodium solution (100mM) is a nucleotide precursor in cells for DNA synthesis. Deoxyguanosine triphosphate trisodium salt is used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification.
    Deoxyguanosine triphosphate (trisodium) solution (100mM)
  • HY-145934A
    UDP-GlcNAz disodium 1611490-64-2 99.74%
    UDP-GlcNAz disodium (UDP-N-azidoacetylgalactosamine disodium) is the analogue of UDP-GlcNAc (HY-112174). UDP-GlcNAc is the donor substrate of many N-acetylgalactosaminyltransferases, enzymes which transfer GlcNAc from the nucleotide sugar to a saccharide or peptide acceptor. UDP-GlcNAc (disodium) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    UDP-GlcNAz disodium
  • HY-136648A
    2'-Deoxyadenosine-5'-triphosphate trisodium 54680-12-5 ≥98.0%
    2'-Deoxyadenosine-5'-triphosphate (dATP) trisodium is a nucleotide used in cells for DNA synthesis (or replication), as a substrate of DNA polymerase. 2'-Deoxyadenosine-5'-triphosphate is promising for research of genetic immunodeficiency diseases adenosine deaminase deficiency and purine nucleotide phosphorylase deficiency .
    2'-Deoxyadenosine-5'-triphosphate trisodium
  • HY-141567A
    Pseudouridine 5'-triphosphate trisodium solution (100mM) ≥98.0%
    Pseudouridine 5'-triphosphate (Pseudo-UTP) trisodium solution (100 mM) is a modified ribonucleoside triphosphate. Pseudouridine 5'-triphosphate trisodium solution (100 mM) is substituted for UTP to improve the stability and translation efficiency of mRNA and reduce immunogenicity.
    Pseudouridine 5'-triphosphate trisodium solution (100mM)
  • HY-150145A
    Cy5-UTP sodium (10mM in Water) 99.26%
    Cy5-UTP sodium (10mM in Water) is a cyanine5-labeled UTP analogue that can produce fluorescent probes in vitro transcription reactions with excitation/emission wavelengths of 650/665 nm. Cy5-UTP sodium can be used in FISH, polychromatic fluorescence analysis, especially the two-color expression array combined with Cy5-UTP.
    Cy5-UTP sodium (10mM in Water)
  • HY-101400A
    Deoxycytidine triphosphate (trisodium) solution (100mM) 109909-44-6 99.46%
    Deoxycytidine triphosphate trisodium (dCTP trisodium) solution (100mM) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate trisodium salt has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.
    Deoxycytidine triphosphate (trisodium) solution (100mM)
  • HY-113066C
    Guanosine 5'-diphosphate (sodium), 96% (HPLC) 43139-22-6 99.88%
    Guanosine 5'-diphosphate (sodium), 96% (HPLC) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K+ channel. Guanosine 5'-diphosphate sodium, Type I, 96% (HPLC) is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate (sodium), 96% (HPLC) can be used in the research of inflammation, such as anemia of inflammation (AI).
    Guanosine 5'-diphosphate (sodium), 96% (HPLC)
  • HY-117813
    2-Thiouridine 20235-78-3 99.73%
    2-Thiouridine is an orally active modified nucleobase. 2-Thiouridine stabilizes U:A base pairs and destabilizes U:G wobble base pairs. 2-Thiouridine significantly improves the efficiency and accuracy of nonenzymatic replication of mixed-sequence A/U-containing RNA templates. 2-Thiouridine exhibits antiviral activity against multiple positive-sense single-stranded RNA viruses (DENV2, ZIKV, YFV, JEV, WNV, CHIKV, human coronaviruses ( [HCoV]-229E, HCoV-OC43, SARS-CoV), and MERS-CoV).
    2-Thiouridine
  • HY-34717
    Tetrabutylammonium tetrafluoroborate 429-42-5 99.89%
    Tetrabutylammonium tetrafluoroborate is an inorganic salt commonly used in organic synthesis reactions and electrochemical applications. It is usually used as a catalyst or reagent, and is widely used in the field of organic synthesis, such as fluorination reaction, olefin addition and cyclization reaction, etc. In addition, it can also be used in electrochemical deposition and electroplating, and plays an important role in some electronic devices. Although it has no direct application in the medical field, it plays an important role in chemical research and industrial production.
    Tetrabutylammonium tetrafluoroborate