2-Aminofluorene

Cat. No.: HY-W016433 Purity: 99.90%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

2-Aminofluorene is a synthetic chemical insecticide. 2-Aminofluorene is a genotoxin. 2-Aminofluorene can be used in the research of DNA adduct structure, DNA repair, carcinogenesis, and mutagenesis.

For research use only. We do not sell to patients.

2-Aminofluorene Chemical Structure

CAS No. : 153-78-6

Size	Price	Stock	Quantity

Free Sample (0.1 - 0.5 mg)		Apply Now
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 22	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 22	In-stock	Estimated Time of Arrival: December 31
Solid
1 g	USD 20	In-stock	Estimated Time of Arrival: December 31
5 g	USD 35	Get quote	Estimated Time of Arrival: December 31
10 g		Get quote
50 g		Get quote

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Other Forms of 2-Aminofluorene:

2-Aminofluorene-¹³C Get quote
2-Aminofluorene-d₁₁ Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

2-Aminofluorene is a synthetic chemical insecticide. 2-Aminofluorene is a genotoxin. 2-Aminofluorene can be used in the research of DNA adduct structure, DNA repair, carcinogenesis, and mutagenesis^[1]^[4].

In Vitro

2-Aminofluorene (0-100 μM, 1-5 days) produces a dose-related suppression of the antibody response to sheep erythrocytes (SRBC), DNP-Ficoll, and LPS^[2].
2-Aminofluorene (0-100 μM, 3 days, spleen cells) produces suppression on lymphoproliferative responses to LPS and Con A^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

2-Aminofluorene (60 mg/kg, i.p.) accumulates twice the 2-Aminofluorene-DNA adducts of slow acetylators (A/J) in rapid acetylator mice (C57BL/6J)^[3].
2-Aminofluorene (60 mg/kg, i.p.) forms significantly higher levels of DNA adducts in tumor-target organs than in non-target organs in acetylator congenic hamsters^[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

181.24

Formula

C₁₃H₁₁N

CAS No.

153-78-6

Appearance

Solid

Color

Off-white to light yellow

SMILES

NC1=CC(CC2=C3C=CC=C2)=C3C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (551.75 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.5175 mL	27.5877 mL	55.1755 mL
5 mM	1.1035 mL	5.5175 mL	11.0351 mL
10 mM	0.5518 mL	2.7588 mL	5.5175 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.90%

Select Batch:

Data Sheet (273 KB) SDS (557 KB)

COA (249 KB) HNMR (123 KB) RP-HPLC (94 KB)

Handling Instructions (2659 KB)

References

[1]. Heflich RH, et al. Genetic toxicity of 2-acetylaminofluorene, 2-aminofluorene and some of their metabolites and model metabolites. Mutat Res. 1994 Oct;318(2):73-114. [Content Brief]

[2]. Kim BS, et al. Immunosuppressive effects of 2-acetylaminofluorene and 2-aminofluorene on murine splenocytes culture. Drug Chem Toxicol. 1989 Sep-Dec;12(3-4):297-311. [Content Brief]

[3]. Levy GN, et al. 2-Aminofluorene-DNA adduct formation in acetylator congenic mouse lines. Carcinogenesis. 1989 Apr;10(4):705-9. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	5.5175 mL	27.5877 mL	55.1755 mL	137.9386 mL
	5 mM	1.1035 mL	5.5175 mL	11.0351 mL	27.5877 mL
	10 mM	0.5518 mL	2.7588 mL	5.5175 mL	13.7939 mL
	15 mM	0.3678 mL	1.8392 mL	3.6784 mL	9.1959 mL
	20 mM	0.2759 mL	1.3794 mL	2.7588 mL	6.8969 mL
	25 mM	0.2207 mL	1.1035 mL	2.2070 mL	5.5175 mL
	30 mM	0.1839 mL	0.9196 mL	1.8392 mL	4.5980 mL
	40 mM	0.1379 mL	0.6897 mL	1.3794 mL	3.4485 mL
	50 mM	0.1104 mL	0.5518 mL	1.1035 mL	2.7588 mL
	60 mM	0.0920 mL	0.4598 mL	0.9196 mL	2.2990 mL
	80 mM	0.0690 mL	0.3448 mL	0.6897 mL	1.7242 mL
	100 mM	0.0552 mL	0.2759 mL	0.5518 mL	1.3794 mL

2-Aminofluorene Related Classifications

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2-Aminofluorene153-78-6DNA/RNA SynthesisSheep erythrocytesSRBCLPSDNA adductacetylatorInhibitorinhibitorinhibit

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