2. Cell Cycle/DNA Damage
  3. DNA/RNA Synthesis
  4. 2-Aminofluorene

2-Aminofluorene is a synthetic chemical insecticide. 2-Aminofluorene is a genotoxin. 2-Aminofluorene can be used in the research of DNA adduct structure, DNA repair, carcinogenesis, and mutagenesis.

For research use only. We do not sell to patients.

2-Aminofluorene Chemical Structure

2-Aminofluorene Chemical Structure

CAS No. : 153-78-6

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10 mM * 1 mL in DMSO
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Other Forms of 2-Aminofluorene:

2-Aminofluorene Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

2-Aminofluorene is a synthetic chemical insecticide. 2-Aminofluorene is a genotoxin. 2-Aminofluorene can be used in the research of DNA adduct structure, DNA repair, carcinogenesis, and mutagenesis[1][4].

In Vitro

2-Aminofluorene (0-100 μM, 1-5 days) produces a dose-related suppression of the antibody response to sheep erythrocytes (SRBC), DNP-Ficoll, and LPS[2].
2-Aminofluorene (0-100 μM, 3 days, spleen cells) produces suppression on lymphoproliferative responses to LPS and Con A[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

2-Aminofluorene Related Antibodies
In Vivo

2-Aminofluorene (60 mg/kg, i.p.) accumulates twice the 2-Aminofluorene-DNA adducts of slow acetylators (A/J) in rapid acetylator mice (C57BL/6J)[3].
2-Aminofluorene (60 mg/kg, i.p.) forms significantly higher levels of DNA adducts in tumor-target organs than in non-target organs in acetylator congenic hamsters[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

181.24

Formula

C13H11N
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

NC1=CC(CC2=C3C=CC=C2)=C3C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (551.75 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.5175 mL 27.5877 mL 55.1755 mL
5 mM 1.1035 mL 5.5175 mL 11.0351 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

g

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.90%

COA (249 KB) HNMR (123 KB) RP-HPLC (94 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.5175 mL 27.5877 mL 55.1755 mL 137.9386 mL
5 mM 1.1035 mL 5.5175 mL 11.0351 mL 27.5877 mL
10 mM 0.5518 mL 2.7588 mL 5.5175 mL 13.7939 mL
15 mM 0.3678 mL 1.8392 mL 3.6784 mL 9.1959 mL
20 mM 0.2759 mL 1.3794 mL 2.7588 mL 6.8969 mL
25 mM 0.2207 mL 1.1035 mL 2.2070 mL 5.5175 mL
30 mM 0.1839 mL 0.9196 mL 1.8392 mL 4.5980 mL
40 mM 0.1379 mL 0.6897 mL 1.3794 mL 3.4485 mL
50 mM 0.1104 mL 0.5518 mL 1.1035 mL 2.7588 mL
60 mM 0.0920 mL 0.4598 mL 0.9196 mL 2.2990 mL
80 mM 0.0690 mL 0.3448 mL 0.6897 mL 1.7242 mL
100 mM 0.0552 mL 0.2759 mL 0.5518 mL 1.3794 mL
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2-Aminofluorene Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2-Aminofluorene153-78-6DNA/RNA SynthesisSheep erythrocytesSRBCLPSDNA adductacetylatorInhibitorinhibitorinhibit

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