2-Arachidonoylglycerol-d₈

Cat. No.: HY-W011051S Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

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2-Arachidonoylglycerol-d₈ is the deuterium labeled 2-Arachidonoylglycerol. 2-Arachidonoylglycerol is a second endogenous cannabinoid ligand in the central nervous system.

For research use only. We do not sell to patients.

2-Arachidonoylglycerol-d<sub>8</sub> Chemical Structure

2-Arachidonoylglycerol-d₈ Chemical Structure

CAS No. : 924894-97-3

Size	Price	Stock	Quantity
Solvent
25 μg（258.67 μM * 250 μL in Acetonitrile）	USD 250	In-stock	Estimated Time of Arrival: December 31

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Based on 1 publication(s) in Google Scholar

Other Forms of 2-Arachidonoylglycerol-d₈:

2-Arachidonoylglycerol In-stock

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Biological Activity
Purity & Documentation
References
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Description	2-Arachidonoylglycerol-d₈ is the deuterium labeled 2-Arachidonoylglycerol. 2-Arachidonoylglycerol is a second endogenous cannabinoid ligand in the central nervous system.
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. 2-Arachidonoylglycerol-d₈ Related Antibodies
Molecular Weight	386.59
Formula	C₂₃H₃₀D₈O₄
CAS No.	924894-97-3
Unlabeled CAS	53847-30-6
Appearance	Liquid
Color	Colorless to light yellow
SMILES	OCC(CO)OC(CCC/C([2H])=C([2H])\C/C([2H])=C([2H])\C/C([2H])=C([2H])\C/C([2H])=C([2H])\CCCCC)=O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Solution, -20°C, 2 years
Solvent & Solubility	In Vitro: DMSO : ≥ 10 mg/mL (25.87 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) DMSO : ≥ 10 mg/mL (25.87 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) "≥" means soluble, but saturation unknown. Molarity Calculator Dilution Calculator Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Mass = Concentration × Volume × Molecular Weight Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final) This equation is commonly abbreviated as: C₁V₁ = C₂V₂ Concentration _(start) C1 × Volume _(start) V1 = Concentration _(final) C2 × Volume _(final) V2 In Vivo Dissolution Calculator Please enter the basic information of animal experiments: Dosage mg/kg Animal weight (per animal) g Dosing volume (per animal) μL Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments. Calculation results: Working solution concentration: mg/mL
Purity & Documentation	Purity: ≥98.0% Select Batch: Data Sheet (270 KB) SDS (251 KB) COA (251 KB) Handling Instructions (2659 KB)
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief] [2]. Stella N, et al. A second endogenous cannabinoid that modulates long-term potentiation. Nature. 1997 Aug 21;388(6644):773-8. [Content Brief]

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / DMSO	1 mM	2.5867 mL	12.9336 mL	25.8672 mL	64.6680 mL
	5 mM	0.5173 mL	2.5867 mL	5.1734 mL	12.9336 mL
	10 mM	0.2587 mL	1.2934 mL	2.5867 mL	6.4668 mL
	15 mM	0.1724 mL	0.8622 mL	1.7245 mL	4.3112 mL
	20 mM	0.1293 mL	0.6467 mL	1.2934 mL	3.2334 mL
	25 mM	0.1035 mL	0.5173 mL	1.0347 mL	2.5867 mL