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  3. 2-Bromo-5-nitropyridine

2-Bromo-5-nitropyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

For research use only. We do not sell to patients.

2-Bromo-5-nitropyridine Chemical Structure

2-Bromo-5-nitropyridine Chemical Structure

CAS No. : 4487-59-6

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Based on 1 publication(s) in Google Scholar

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Description

2-Bromo-5-nitropyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

In Vitro

2-Bromo-5-nitropyridine was used in preparation of boc-protected (piperazin-1-ylmethyl)biaryls via microwave-mediated Suzuki-Miyaura coupling with (boc-piperazin-1-ylmethyl)phenylboronic acid pinacol esters. It was also used in the synthesis of 2-pyridyl analogs. Substituted 5-nitro-2-ethylpyridines were synthesized by the Sonogashira reaction of 2-bromo-5-5-nitropyridine with terminal acetylenes.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

202.99

Formula

C5H3BrN2O2

CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

BrC1=NC=C([N+]([O-])=O)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (492.64 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.9264 mL 24.6318 mL 49.2635 mL
5 mM 0.9853 mL 4.9264 mL 9.8527 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.92%

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.9264 mL 24.6318 mL 49.2635 mL 123.1588 mL
5 mM 0.9853 mL 4.9264 mL 9.8527 mL 24.6318 mL
10 mM 0.4926 mL 2.4632 mL 4.9264 mL 12.3159 mL
15 mM 0.3284 mL 1.6421 mL 3.2842 mL 8.2106 mL
20 mM 0.2463 mL 1.2316 mL 2.4632 mL 6.1579 mL
25 mM 0.1971 mL 0.9853 mL 1.9705 mL 4.9264 mL
30 mM 0.1642 mL 0.8211 mL 1.6421 mL 4.1053 mL
40 mM 0.1232 mL 0.6158 mL 1.2316 mL 3.0790 mL
50 mM 0.0985 mL 0.4926 mL 0.9853 mL 2.4632 mL
60 mM 0.0821 mL 0.4105 mL 0.8211 mL 2.0526 mL
80 mM 0.0616 mL 0.3079 mL 0.6158 mL 1.5395 mL
100 mM 0.0493 mL 0.2463 mL 0.4926 mL 1.2316 mL
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2-Bromo-5-nitropyridine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
2-Bromo-5-nitropyridine
Cat. No.:
HY-W007858
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