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2-Deoxy-D-glucose 6-phosphate disodium 

Cat. No.: HY-139409A Purity: ≥98.0%
COA Handling Instructions

2-Deoxy-D-glucose 6-phosphate disodium, a derivative of 2-Deoxy-D-glucose, is produced in mammalian cells by the action of hexokinase on 2-DG. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase.

For research use only. We do not sell to patients.

2-Deoxy-D-glucose 6-phosphate disodium Chemical Structure

2-Deoxy-D-glucose 6-phosphate disodium Chemical Structure

CAS No. : 33068-19-8

Size Price Stock Quantity
5 mg USD 96 In-stock
10 mg USD 150 In-stock
25 mg USD 290 In-stock
50 mg USD 460 In-stock
100 mg   Get quote  
200 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

2-Deoxy-D-glucose 6-phosphate disodium, a derivative of 2-Deoxy-D-glucose, is produced in mammalian cells by the action of hexokinase on 2-DG. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase[1].

Molecular Weight

288.10

Formula

C6H11Na2O8P

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=P(O[Na])(O[Na])OC[C@@H](O)[C@@H](O)[C@H](O)CC=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 250 mg/mL (867.75 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.4710 mL 17.3551 mL 34.7102 mL
5 mM 0.6942 mL 3.4710 mL 6.9420 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 3.4710 mL 17.3551 mL 34.7102 mL 86.7754 mL
5 mM 0.6942 mL 3.4710 mL 6.9420 mL 17.3551 mL
10 mM 0.3471 mL 1.7355 mL 3.4710 mL 8.6775 mL
15 mM 0.2314 mL 1.1570 mL 2.3140 mL 5.7850 mL
20 mM 0.1736 mL 0.8678 mL 1.7355 mL 4.3388 mL
25 mM 0.1388 mL 0.6942 mL 1.3884 mL 3.4710 mL
30 mM 0.1157 mL 0.5785 mL 1.1570 mL 2.8925 mL
40 mM 0.0868 mL 0.4339 mL 0.8678 mL 2.1694 mL
50 mM 0.0694 mL 0.3471 mL 0.6942 mL 1.7355 mL
60 mM 0.0579 mL 0.2893 mL 0.5785 mL 1.4463 mL
80 mM 0.0434 mL 0.2169 mL 0.4339 mL 1.0847 mL
100 mM 0.0347 mL 0.1736 mL 0.3471 mL 0.8678 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
2-Deoxy-D-glucose 6-phosphate disodium
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