2. Cell Cycle/DNA Damage
  3. DNA/RNA Synthesis
  4. 2'-Deoxyadenosine 5'-di-phos-phate disodium

2'-Deoxyadenosine 5'-di-phos-phate disodium  (Synonyms: dADP disodium)

Cat. No.: HY-W010854 Purity: ≥95.0%
SDS COA Handling Instructions Technical Support

2'-Deoxyadenosine 5'-di-phos-phate disodium (dADP disodium) is an inhibitor of bacterial poly(A) polymerase. It can be used to synthesize deoxyadenosine oligonucleotides with Escherichia coli polynucleotide phosphorylase and other enzymes.

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2'-Deoxyadenosine 5'-di-phos-phate disodium Chemical Structure

2'-Deoxyadenosine 5'-di-phos-phate disodium Chemical Structure

CAS No. : 72003-83-9

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2'-Deoxyadenosine 5'-di-phos-phate disodium Related Antibodies

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Description

2'-Deoxyadenosine 5'-di-phos-phate disodium (dADP disodium) is an inhibitor of bacterial poly(A) polymerase. It can be used to synthesize deoxyadenosine oligonucleotides with Escherichia coli polynucleotide phosphorylase and other enzymes[1].

Molecular Weight

455.17

Formula

C10H13N5Na2O9P2
CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

O[C@H]1C[C@H](N2C(N=CN=C3N)=C3N=C2)O[C@@H]1COP(OP(O)(O[Na])=O)(O[Na])=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

H2O : 250 mg/mL (549.25 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1970 mL 10.9849 mL 21.9698 mL
5 mM 0.4394 mL 2.1970 mL 4.3940 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

SDS (420 KB)

COA (254 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.1970 mL 10.9849 mL 21.9698 mL 54.9245 mL
5 mM 0.4394 mL 2.1970 mL 4.3940 mL 10.9849 mL
10 mM 0.2197 mL 1.0985 mL 2.1970 mL 5.4925 mL
15 mM 0.1465 mL 0.7323 mL 1.4647 mL 3.6616 mL
20 mM 0.1098 mL 0.5492 mL 1.0985 mL 2.7462 mL
25 mM 0.0879 mL 0.4394 mL 0.8788 mL 2.1970 mL
30 mM 0.0732 mL 0.3662 mL 0.7323 mL 1.8308 mL
40 mM 0.0549 mL 0.2746 mL 0.5492 mL 1.3731 mL
50 mM 0.0439 mL 0.2197 mL 0.4394 mL 1.0985 mL
60 mM 0.0366 mL 0.1831 mL 0.3662 mL 0.9154 mL
80 mM 0.0275 mL 0.1373 mL 0.2746 mL 0.6866 mL
100 mM 0.0220 mL 0.1098 mL 0.2197 mL 0.5492 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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2'-Deoxyadenosine 5'-di-phos-phate disodium Related Classifications

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Keywords:

2'-Deoxyadenosine 5'-di-phos-phate disodium72003-83-9dADP disodiumDNA/RNA SynthesisdADPpoly(A) polymeraseInhibitorinhibitorinhibit

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