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2-Iodoaniline  (Synonyms: 2-Iodophenylamine)

Cat. No.: HY-W007318 Purity: 99.98%
SDS COA Handling Instructions

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2-Iodoaniline (2-Iodophenylamine) is an aniline derivative, and has potential hepatotoxic and nephrotoxic activity.

For research use only. We do not sell to patients.

2-Iodoaniline Chemical Structure

2-Iodoaniline Chemical Structure

CAS No. : 615-43-0

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Based on 1 publication(s) in Google Scholar

Other Forms of 2-Iodoaniline:

2-Iodoaniline Related Antibodies

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Description

2-Iodoaniline (2-Iodophenylamine) is an aniline derivative, and has potential hepatotoxic and nephrotoxic activity[1].

In Vivo

2-Iodoaniline (1.0 mM/kg, 1.25 mM/kg for 2.5 mL; i.p.; single dose) exhibits hepatotoxic and nephrotoxic potential in Male Fischer 344 rats[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Fischer 344 rats (185-260 g)[1]
Dosage: 1.0 mM/kg, 1.25 mM/kg for 2.5 mL
Administration: Intraperitoneal injection; single dose; monitored renal and hepatic function 24 h after treatment
Result: Induced oliguria, diminished kidney weight, tubular casts and decreased renal cortical slice accumulation of organic anions.
Elevated plasma ALT/GPT activity and altered morphology in the centrilobular region.
Molecular Weight

219.02

Formula

C6H6IN
CAS No.
Appearance

Solid

Color

White to light brown

SMILES

IC1=CC=CC=C1N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (456.58 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.5658 mL 22.8290 mL 45.6579 mL
5 mM 0.9132 mL 4.5658 mL 9.1316 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

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Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.98%

SDS (393 KB)

COA (249 KB) HNMR (225 KB) RP-HPLC (402 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.5658 mL 22.8290 mL 45.6579 mL 114.1448 mL
5 mM 0.9132 mL 4.5658 mL 9.1316 mL 22.8290 mL
10 mM 0.4566 mL 2.2829 mL 4.5658 mL 11.4145 mL
15 mM 0.3044 mL 1.5219 mL 3.0439 mL 7.6097 mL
20 mM 0.2283 mL 1.1414 mL 2.2829 mL 5.7072 mL
25 mM 0.1826 mL 0.9132 mL 1.8263 mL 4.5658 mL
30 mM 0.1522 mL 0.7610 mL 1.5219 mL 3.8048 mL
40 mM 0.1141 mL 0.5707 mL 1.1414 mL 2.8536 mL
50 mM 0.0913 mL 0.4566 mL 0.9132 mL 2.2829 mL
60 mM 0.0761 mL 0.3805 mL 0.7610 mL 1.9024 mL
80 mM 0.0571 mL 0.2854 mL 0.5707 mL 1.4268 mL
100 mM 0.0457 mL 0.2283 mL 0.4566 mL 1.1414 mL
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2-Iodoaniline Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2-Iodoaniline615-43-02-IodophenylamineOthersaniline derivativehepatotoxic activitynephrotoxic activityInhibitorinhibitorinhibit

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