2-(Methylsulfonyl)ethyl n-succinimidyl carbonate

Cat. No.: HY-W319374 Purity: ≥97.0%: FAQs
Data Sheet SDS COA Handling Instructions

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2-(Methylsulfonyl)ethyl n-succinimidyl carbonate is a protein crosslinker. 2-(Methylsulfonyl)ethyl n-succinimidyl carbonate has amino protective function.

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2-(Methylsulfonyl)ethyl n-succinimidyl carbonate Chemical Structure

CAS No. : 57903-15-8

Size	Price	Stock	Quantity
100 mg	USD 230	In-stock	Estimated Time of Arrival: December 31
250 mg	USD 460	In-stock	Estimated Time of Arrival: December 31
500 mg		Get quote
1 g		Get quote

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Description

2-(Methylsulfonyl)ethyl n-succinimidyl carbonate is a protein crosslinker. 2-(Methylsulfonyl)ethyl n-succinimidyl carbonate has amino protective function^[1].

Molecular Weight

265.24

Formula

C₈H₁₁NO₇S

CAS No.

57903-15-8

Appearance

Solid

Color

White to off-white

SMILES

CS(=O)(=O)CCOC(=O)ON1C(=O)CCC1=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (188.51 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.7702 mL	18.8509 mL	37.7017 mL
5 mM	0.7540 mL	3.7702 mL	7.5403 mL
10 mM	0.3770 mL	1.8851 mL	3.7702 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥97.0%

Select Batch:

Data Sheet (270 KB) SDS (393 KB)

COA (251 KB) HNMR (218 KB)

Handling Instructions (2659 KB)

References

[1]. Joerg Lahann, et al. Selective release of polymer-encapsulated ingredients, especially drugs, comprises crosslinking the polymer chains with cleavable bridging molecules. Patent. DE19905793.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.7702 mL	18.8509 mL	37.7017 mL	94.2543 mL
	5 mM	0.7540 mL	3.7702 mL	7.5403 mL	18.8509 mL
	10 mM	0.3770 mL	1.8851 mL	3.7702 mL	9.4254 mL
	15 mM	0.2513 mL	1.2567 mL	2.5134 mL	6.2836 mL
	20 mM	0.1885 mL	0.9425 mL	1.8851 mL	4.7127 mL
	25 mM	0.1508 mL	0.7540 mL	1.5081 mL	3.7702 mL
	30 mM	0.1257 mL	0.6284 mL	1.2567 mL	3.1418 mL
	40 mM	0.0943 mL	0.4713 mL	0.9425 mL	2.3564 mL
	50 mM	0.0754 mL	0.3770 mL	0.7540 mL	1.8851 mL
	60 mM	0.0628 mL	0.3142 mL	0.6284 mL	1.5709 mL
	80 mM	0.0471 mL	0.2356 mL	0.4713 mL	1.1782 mL
	100 mM	0.0377 mL	0.1885 mL	0.3770 mL	0.9425 mL