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  4. 2-Pyrazinecarboxylic acid

2-Pyrazinecarboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

For research use only. We do not sell to patients.

2-Pyrazinecarboxylic acid Chemical Structure

2-Pyrazinecarboxylic acid Chemical Structure

CAS No. : 98-97-5

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10 mM * 1 mL in DMSO
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Based on 1 publication(s) in Google Scholar

Other Forms of 2-Pyrazinecarboxylic acid:

2-Pyrazinecarboxylic acid Related Antibodies

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Description

2-Pyrazinecarboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

In Vitro

Pyrazinecarboxylic acid is an active metabolite of pyrazinamide. Pyrazinamidean is an anti-tubercular agent. In this model for the evaluation of the effects of uricosuric agents, the urinary excretion of pyrazinecarboxylic acid was decreased by probenecid and indic ated an inverse correlation between urinary excretion of urate and pyrazinecarboxylic acid. In the in vitro study, the treatment of the vesicles of rat renal brush-border membrane with pyrazinecarboxylic acid produced an increased urate uptake, which was inhibited by uricosuric agents. PZA (pyrazinamide) is con verted to pyrazinecarboxylic acid (POA) in plant cells, suppressing the activity of 1-aminocyclopropane-1-carboxylic acid oxidase (ACO), the enzyme catalysing the final step of ethylene formation.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

2-Pyrazinecarboxylic acid Related Antibodies
Molecular Weight

124.10

Formula

C5H4N2O2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)C1=NC=CN=C1
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (402.90 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 8.0580 mL 40.2901 mL 80.5802 mL
5 mM 1.6116 mL 8.0580 mL 16.1160 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 8.0580 mL 40.2901 mL 80.5802 mL 201.4504 mL
5 mM 1.6116 mL 8.0580 mL 16.1160 mL 40.2901 mL
10 mM 0.8058 mL 4.0290 mL 8.0580 mL 20.1450 mL
15 mM 0.5372 mL 2.6860 mL 5.3720 mL 13.4300 mL
20 mM 0.4029 mL 2.0145 mL 4.0290 mL 10.0725 mL
25 mM 0.3223 mL 1.6116 mL 3.2232 mL 8.0580 mL
30 mM 0.2686 mL 1.3430 mL 2.6860 mL 6.7150 mL
40 mM 0.2015 mL 1.0073 mL 2.0145 mL 5.0363 mL
50 mM 0.1612 mL 0.8058 mL 1.6116 mL 4.0290 mL
60 mM 0.1343 mL 0.6715 mL 1.3430 mL 3.3575 mL
80 mM 0.1007 mL 0.5036 mL 1.0073 mL 2.5181 mL
100 mM 0.0806 mL 0.4029 mL 0.8058 mL 2.0145 mL
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2-Pyrazinecarboxylic acid Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2-Pyrazinecarboxylic acid98-97-5Biochemical Assay Reagentsbiochemical reagentbiological materialorganic compoundlife scienceInhibitorinhibitorinhibit

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