1. GPCR/G Protein Neuronal Signaling Immunology/Inflammation
  2. Histamine Receptor
  3. 2-Pyridylethylamine hydrochloride

2-Pyridylethylamine is a histamine-1 (H1R) receptor agonist. 2-Pyridylethylamine can reduce the joint injury induced by formalin in rats. 2-Pyridylethylamine can be used to study the spinal cord release of neuropeptide (NPY) .

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2-Pyridylethylamine hydrochloride Chemical Structure

2-Pyridylethylamine hydrochloride Chemical Structure

CAS No. : 3343-39-3

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Solid
5 mg In-stock
10 mg In-stock
50 mg In-stock
100 mg In-stock
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Description

2-Pyridylethylamine is a histamine-1 (H1R) receptor agonist. 2-Pyridylethylamine can reduce the joint injury induced by formalin in rats. 2-Pyridylethylamine can be used to study the spinal cord release of neuropeptide (NPY) [1].

Molecular Weight

195.09

Formula

C7H12Cl2N2

CAS No.
Appearance

Solid

Color

Off-white to light brown

SMILES

NCCC1=CC=CC=N1.Cl.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (640.72 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.1258 mL 25.6288 mL 51.2576 mL
5 mM 1.0252 mL 5.1258 mL 10.2515 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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mg/kg

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.1258 mL 25.6288 mL 51.2576 mL 128.1440 mL
5 mM 1.0252 mL 5.1258 mL 10.2515 mL 25.6288 mL
10 mM 0.5126 mL 2.5629 mL 5.1258 mL 12.8144 mL
15 mM 0.3417 mL 1.7086 mL 3.4172 mL 8.5429 mL
20 mM 0.2563 mL 1.2814 mL 2.5629 mL 6.4072 mL
25 mM 0.2050 mL 1.0252 mL 2.0503 mL 5.1258 mL
30 mM 0.1709 mL 0.8543 mL 1.7086 mL 4.2715 mL
40 mM 0.1281 mL 0.6407 mL 1.2814 mL 3.2036 mL
50 mM 0.1025 mL 0.5126 mL 1.0252 mL 2.5629 mL
60 mM 0.0854 mL 0.4271 mL 0.8543 mL 2.1357 mL
80 mM 0.0641 mL 0.3204 mL 0.6407 mL 1.6018 mL
100 mM 0.0513 mL 0.2563 mL 0.5126 mL 1.2814 mL
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2-Pyridylethylamine hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
2-Pyridylethylamine hydrochloride
Cat. No.:
HY-107565
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