20-Deoxocarnosol

Name: 20-Deoxocarnosol
Brand: MedChemExpress
SKU: HY-122944
Rating: 4.5 (1 reviews)

Cat. No.: HY-122944 Purity: ≥98.0%: FAQs
Data Sheet
SDS

COA
Handling Instructions Technical Support

20-Deoxocarnosol (compound 7) is a potent anti-cancer agent that can be found in the roots of Salvia deserta. 20-Deoxocarnosol shows cytotoxicity in cancer cells.

For research use only. We do not sell to patients.

20-Deoxocarnosol Chemical Structure

CAS No. : 94529-97-2

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	Get quote
10 mg	Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
References
Customer Review

Description

20-Deoxocarnosol (compound 7) is a potent anti-cancer agent that can be found in the roots of Salvia deserta. 20-Deoxocarnosol shows cytotoxicity in cancer cells^[1].

In Vitro

Deoxocarnosol (compound 7) (0-40 μM) shows cytotoxicity with IC₅₀ values of ?40, 32.70, 15.15, ?40, 24.79, ?40 μM for :A549, SMMC-7721, HL-60, MCF-7, SW480, BEAS-2B cells, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay^[1]

Cell Line:	A549, SMMC-7721, HL-60, MCF-7, SW480, BEAS-2B cells
Concentration:	0-40 µM
Incubation Time:
Result:	Showed cytotoxicity with IC₅₀ values of ˃40, 32.70, 15.15, ˃40, 24.79, ˃40 µM for :A549, SMMC-7721, HL-60, MCF-7, SW480, BEAS-2B cells, respectively.

Molecular Weight

316.43

Formula

C₂₀H₂₈O₃

CAS No.

94529-97-2

Appearance

Solid

Color

Light yellow to yellow

SMILES

OC1=C2[C@@](CO3)(CCCC(C)4C)[C@@]4([H])C[C@@]3([H])C2=CC(C(C)C)=C1O

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : ≥ 50 mg/mL (158.01 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.1603 mL	15.8013 mL	31.6026 mL
5 mM	0.6321 mL	3.1603 mL	6.3205 mL
10 mM	0.3160 mL	1.5801 mL	3.1603 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (280 KB) SDS (252 KB)

COA (259 KB)

Handling Instructions (2659 KB)

References

[1]. Guijuan Zheng, et al. Spirodesertols A and B, two highly modified spirocyclic diterpenoids with an unprecedented 6-isopropyl-3H-spiro[benzofuran-2,1′-cyclohexane] motif from Salvia deserta. Org. Chem. Front., 2020,7, 3137-3145.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.1603 mL	15.8013 mL	31.6026 mL	79.0064 mL
	5 mM	0.6321 mL	3.1603 mL	6.3205 mL	15.8013 mL
	10 mM	0.3160 mL	1.5801 mL	3.1603 mL	7.9006 mL
	15 mM	0.2107 mL	1.0534 mL	2.1068 mL	5.2671 mL
	20 mM	0.1580 mL	0.7901 mL	1.5801 mL	3.9503 mL
	25 mM	0.1264 mL	0.6321 mL	1.2641 mL	3.1603 mL
	30 mM	0.1053 mL	0.5267 mL	1.0534 mL	2.6335 mL
	40 mM	0.0790 mL	0.3950 mL	0.7901 mL	1.9752 mL
	50 mM	0.0632 mL	0.3160 mL	0.6321 mL	1.5801 mL
	60 mM	0.0527 mL	0.2634 mL	0.5267 mL	1.3168 mL
	80 mM	0.0395 mL	0.1975 mL	0.3950 mL	0.9876 mL
	100 mM	0.0316 mL	0.1580 mL	0.3160 mL	0.7901 mL