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  6. 20-Deoxyingenol 3-angelate

20-Deoxyingenol 3-angelate (DI3A) increases degranulation and interferon-gamma secretion of NK cells. 20-Deoxyingenol 3-angelate enhances NK cell tumoricidal activity.

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20-Deoxyingenol 3-angelate Chemical Structure

20-Deoxyingenol 3-angelate Chemical Structure

CAS No. : 75567-38-3

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Based on 1 publication(s) in Google Scholar

20-Deoxyingenol 3-angelate Related Antibodies

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Description

20-Deoxyingenol 3-angelate (DI3A) increases degranulation and interferon-gamma secretion of NK cells. 20-Deoxyingenol 3-angelate enhances NK cell tumoricidal activity[1].

Cellular Effect
Cell Line Type Value Description References
HeLa IC50
> 10 μM
Compound: 12
Cytotoxicity against human HeLa cells assessed as cell growth inhibition incubated for 68 hrs by MTT assay
Cytotoxicity against human HeLa cells assessed as cell growth inhibition incubated for 68 hrs by MTT assay
[PMID: 34665635]
HepG2 IC50
> 10 μM
Compound: 12
Cytotoxicity against human HepG2 cells assessed as cell growth inhibition incubated for 68 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as cell growth inhibition incubated for 68 hrs by MTT assay
[PMID: 34665635]
MT4 CC50
> 9.7 μM
Compound: 17
Cytotoxicity against human MT4 cells after 3 days by CytoTox-Glo assay
Cytotoxicity against human MT4 cells after 3 days by CytoTox-Glo assay
[PMID: 30031972]
PC-3 IC50
> 10 μM
Compound: 12
Cytotoxicity against human PC-3 cells assessed as cell growth inhibition incubated for 68 hrs by MTT assay
Cytotoxicity against human PC-3 cells assessed as cell growth inhibition incubated for 68 hrs by MTT assay
[PMID: 34665635]
SK-MEL-28 IC50
> 10 μM
Compound: 12
Cytotoxicity against human SK-MEL-28 cells assessed as cell growth inhibition incubated for 68 hrs by MTT assay
Cytotoxicity against human SK-MEL-28 cells assessed as cell growth inhibition incubated for 68 hrs by MTT assay
[PMID: 34665635]
Molecular Weight

414.53

Formula

C25H34O5
CAS No.
SMILES

O[C@@]12[C@]3(C=C([C@@H]2OC(/C(C)=C\C)=O)C)C([C@](C=C([C@H]1O)C)([H])[C@@]4([H])[C@@](C4(C)C)([H])C[C@H]3C)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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20-Deoxyingenol 3-angelate Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

20-Deoxyingenol 3-angelate75567-38-3OthersNatural ProductsInhibitorinhibitorinhibit

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