2. Immunology/Inflammation Vitamin D Related/Nuclear Receptor
  3. Glucocorticoid Receptor
  4. 21-Desacetyldeflazacort-d5

21-Desacetyldeflazacort-d5  (Synonyms: 21-desDFZ-d5)

Cat. No.: HY-100085S Purity: 99.34%
SDS COA Handling Instructions

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21-Desacetyldeflazacort-d5 is the deuterium labeled 21-Desacetyldeflazacort[1].

For research use only. We do not sell to patients.

21-Desacetyldeflazacort-d<sub>5</sub> Chemical Structure

21-Desacetyldeflazacort-d5 Chemical Structure

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1 mg USD 330 In-stock
5 mg USD 930 Get quote
10 mg USD 1480 Get quote
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Based on 1 publication(s) in Google Scholar

Other Forms of 21-Desacetyldeflazacort-d5:

21-Desacetyldeflazacort-d5 Related Antibodies

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Description

21-Desacetyldeflazacort-d5 is the deuterium labeled 21-Desacetyldeflazacort[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

21-Desacetyldeflazacort-d5 Related Antibodies
Molecular Weight

404.51

Formula

C23H24D5NO5
Unlabeled CAS

13649-57-5
Appearance

Solid

Color

White to off-white

SMILES

O=C(C=C[C@]12C)C=C2CC[C@@H]3[C@]1([H])[C@@H](O)C[C@@]4(C)[C@H]3C[C@@H](O5)[C@@]4(C(C([2H])([2H])O)=O)N=C5C([2H])([2H])[2H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMF : ≥ 30 mg/mL (74.16 mM)

DMSO : ≥ 30 mg/mL (74.16 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMF : ≥ 30 mg/mL (74.16 mM)

DMSO : ≥ 30 mg/mL (74.16 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Ethanol : ≥ 1 mg/mL (2.47 mM)

Ethanol : ≥ 1 mg/mL (2.47 mM)

DMSO:PBS(pH 7.2) (1:3) : ≥ 0.25 mg/mL (0.62 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4721 mL 12.3606 mL 24.7213 mL
5 mM 0.4944 mL 2.4721 mL 4.9443 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Dosing volume
(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol / Ethanol / DMF / DMSO / DMF / DMSO 1 mM 2.4721 mL 12.3606 mL 24.7213 mL 61.8032 mL
DMF / DMSO / DMF / DMSO 5 mM 0.4944 mL 2.4721 mL 4.9443 mL 12.3606 mL
10 mM 0.2472 mL 1.2361 mL 2.4721 mL 6.1803 mL
15 mM 0.1648 mL 0.8240 mL 1.6481 mL 4.1202 mL
20 mM 0.1236 mL 0.6180 mL 1.2361 mL 3.0902 mL
25 mM 0.0989 mL 0.4944 mL 0.9889 mL 2.4721 mL
30 mM 0.0824 mL 0.4120 mL 0.8240 mL 2.0601 mL
40 mM 0.0618 mL 0.3090 mL 0.6180 mL 1.5451 mL
50 mM 0.0494 mL 0.2472 mL 0.4944 mL 1.2361 mL
60 mM 0.0412 mL 0.2060 mL 0.4120 mL 1.0301 mL
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21-Desacetyldeflazacort-d5 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

21-Desacetyldeflazacort-d521-desDFZ-d5Glucocorticoid ReceptorInhibitorinhibitorinhibit

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