2. Immunology/Inflammation
  3. Galectin
  4. (2S)-Selvigaltin

(2S)-Selvigaltin is the S-enantiomer of Selvigaltin (HY-147041). Selvigaltin is an orally active galectin-3 (Gal-3) inhibitor.

For research use only. We do not sell to patients.

(2S)-Selvigaltin Chemical Structure

(2S)-Selvigaltin Chemical Structure

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Other Forms of (2S)-Selvigaltin:

(2S)-Selvigaltin Related Antibodies

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Description

(2S)-Selvigaltin is the S-enantiomer of Selvigaltin (HY-147041). Selvigaltin is an orally active galectin-3 (Gal-3) inhibitor[1].

IC50 & Target

Galectin-3

 

Molecular Weight

533.32

Formula

C19H16BrF3N4O4S
SMILES

O[C@@H]([C@@H](O1)SC2=CN=CC(Br)=C2)[C@](N3C=C(C(C=C4F)=CC(F)=C4F)N=N3)([H])[C@H]([C@H]1CO)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (46.88 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8750 mL 9.3752 mL 18.7505 mL
5 mM 0.3750 mL 1.8750 mL 3.7501 mL
View the Complete Stock Solution Preparation Table

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

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C2

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V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.8750 mL 9.3752 mL 18.7505 mL 46.8762 mL
5 mM 0.3750 mL 1.8750 mL 3.7501 mL 9.3752 mL
10 mM 0.1875 mL 0.9375 mL 1.8750 mL 4.6876 mL
15 mM 0.1250 mL 0.6250 mL 1.2500 mL 3.1251 mL
20 mM 0.0938 mL 0.4688 mL 0.9375 mL 2.3438 mL
25 mM 0.0750 mL 0.3750 mL 0.7500 mL 1.8750 mL
30 mM 0.0625 mL 0.3125 mL 0.6250 mL 1.5625 mL
40 mM 0.0469 mL 0.2344 mL 0.4688 mL 1.1719 mL
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(2S)-Selvigaltin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(2S)-Selvigaltin(2S)-GB1211Galectinenantiomerorally activeInhibitorinhibitorinhibit

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(2S)-Selvigaltin
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