1. Natural Products
  2. Disease Research Fields Plants Terpenoids
  3. Polyporaceae Cancer Triterpenes
  4. Poria cocos
  5. 3-Epidehydropachymic acid

3-Epidehydropachymic acid, a lanostane triterpenoid, shows totoxicity effect against human acute monocytic leukemia cell line THP-1 (IC50=52.51 μM).

For research use only. We do not sell to patients.

3-Epidehydropachymic acid Chemical Structure

3-Epidehydropachymic acid Chemical Structure

CAS No. : 168293-15-0

Size Price Stock
1 mg Ask For Quote & Lead Time

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

3-Epidehydropachymic acid, a lanostane triterpenoid, shows totoxicity effect against human acute monocytic leukemia cell line THP-1 (IC50=52.51 μM)[1].

Molecular Weight

526.75

Formula

C33H50O5

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@]12[C@@]([C@@]([C@@H](C1)O)([H])[C@H](C(O)=O)CCC(C(C)C)=C)(CC=C3C2=CC[C@]4([H])[C@@]3(CC[C@H](C4(C)C)OC(C)=O)C)C

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 28 mg/mL (53.16 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8984 mL 9.4922 mL 18.9843 mL
5 mM 0.3797 mL 1.8984 mL 3.7969 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.8984 mL 9.4922 mL 18.9843 mL 47.4608 mL
5 mM 0.3797 mL 1.8984 mL 3.7969 mL 9.4922 mL
10 mM 0.1898 mL 0.9492 mL 1.8984 mL 4.7461 mL
15 mM 0.1266 mL 0.6328 mL 1.2656 mL 3.1641 mL
20 mM 0.0949 mL 0.4746 mL 0.9492 mL 2.3730 mL
25 mM 0.0759 mL 0.3797 mL 0.7594 mL 1.8984 mL
30 mM 0.0633 mL 0.3164 mL 0.6328 mL 1.5820 mL
40 mM 0.0475 mL 0.2373 mL 0.4746 mL 1.1865 mL
50 mM 0.0380 mL 0.1898 mL 0.3797 mL 0.9492 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
3-Epidehydropachymic acid
Cat. No.:
HY-N8390
Quantity:
MCE Japan Authorized Agent: