3-Epiglycyrrhetinic acid-d₃  (Synonyms: 3α-Glycyrrhetic acid-d₃)

3-Epiglycyrrhetinic acid-d3 (3α-Glycyrrhetic acid-d3) is the deuterium-labeled 3-Epiglycyrrhetinic acid. 3-Epiglycyrrhetinic acid is a derivative of glycyrrhetic acid. Glycyrrhetic acid and its derivative are considered to have anti-inflammatory, anti-ulcer, and antiviral activities^[1][2].

473.70

C₃₀H₄₃D₃O₄

Solid

White to off-white

C[C@]12[C@@]3(C)C([C@]4([C@@](CC[C@@](C4)(C(O)=O)C)(C)CC3)[H])=CC([C@@]1([C@]5(C)[C@@]([H])(CC2)C([C@]([2H])(O)C([2H])(C5)[2H])(C)C)[H])=O

Room temperature in continental US; may vary elsewhere.

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  [Content Brief]

  [2]. Isbrucker RA, et al., Risk and safety assessment on the consumption of Licorice root (Glycyrrhiza sp.), its extract and powder as a food ingredient, with emphasis on the pharmacology and toxicology of glycyrrhizin. Regul Toxicol Pharmacol. 2006 Dec;46(3):167-92.  [Content Brief]